To the Question of the Quality-of-Life Peculiarities in Men Under 60 Years Old With Urination Disturbances in the Acute and Subacute of Myocardial Infarction Periods

Abstract

Relevance. Changes in the quality of life associated with heart failure (HF) in young and mid-dle-aged men with urological pathology and myocardial infarction (MI) are not well under-stood. Aim. To evaluate changes in the quality of life (QL) indicator associated with heart failure (HF) in men under 60 years old with MI and acute urinary retention (AUR) to improve prevention and outcomes. Material and methods. The study included men aged 19-60 years old with type I MI. Patients are divided into two age-comparable groups: I - the study group, with AUR - 22 patients; II - control, without it - 633 patients. A comparative analysis of the QL indicator associated with HF (HFQL) (V. Ironosov) was performed in the selected groups in the first 48 hours (I) and at the end of the third week (II) of MI. The changes and correlations (C. Spearmen) of HFQL with clinical features, metabolic parameters, central and peripheral hemodynamics were studied. Results. HFQL in patients with AUR (85.7±15.6%) was worse than in the control group (59.4±20.1%; р˂0.0001) in the first hours of MI. At the end of the third week of the disease, no differences between the groups were observed (24.3±11.9 and 18.6±11.9%, respectively; p = 0.06). A positive (72 and 69%) dynamics of HFQL were obtained from the first hours to the end of the subacute MI period in both patient groups (р˂0.0001). In the study group, signifi-cant correlations of HFQL with the size of the left heart chambers, parameters of left ventricle systolic and diastolic function, peripheral hemodynamic, and lipid metabolism parameters were revealed. In the control group, more correlations were found, but their strength was less. Conclusions. The quality of life associated with HF is worse in patients with AUR during the first hours of MI. Dilatation of the left heart chambers, left ventricle systolic and diastolic dys-function, no history of arterial hypertension, and hypocholesterolemia were the most associat-ed with quality of life in the study group. The assessment of HF-related quality of life is use-ful as an adjunct to the examination of patients with MI, starting from the first hours of the disease, for early identification of risk groups for adverse events and chronic HF formation.