To What Extent Is Heroin Used to Relieve Premature Ejaculation and Other Sexual Disorders?

Pera, Giuseppe; Carderi, A.; Marianantoni, Z.; Peris, Filippo; Lentini, M.; Taggi, Franco

doi:10.1016/s1569-9056(06)60182-6

Cited by 2 publications

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“…Finally, in our opinion, these data offer a further contribution to the conjecture, sometimes indicated as the "La Pera hypothesis" [6][7][8][9], which suggests that sexual disorders may be a possible and important cause of the beginning of drug use, and indeed, substance abuse in young males.…”

Section: Figurementioning

confidence: 63%

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Sexual Dysfunction Prior to First Drug Use Among Former Drug Addicts and Its Possible Causal Meaning on Drug Addiction: Preliminary Results

Pera

Carderi

Marianantoni

et al. 2008

The Journal of Sexual Medicine

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Introduction Adolescence is one of the periods in which the risk of initial use of drugs is high. Among the reasons leading to first drug use (FDU), sexual disorders have so far been poorly investigated. Aim To evaluate the prevalence of premature ejaculation, erectile dysfunction, and low sexual desire in former drug addicts in the period prior to FDU; whether or not the former drug addicts claimed that sexual dysfunctions influenced their decision to start illicit drug taking, and whether or not the subjects had sought and used drugs aiming to improve sexual drive. Methods Eighty-six male former drug addicts (18–35 years old) were investigated using a questionnaire. Main Outcome Measures Fisher and Armitage tests. Results Before FDU, 61 (71%) subjects reported having one or more sexual dysfunctions. Only 25 (29%) had no sexual dysfunction prior to FDU. Among those with normal sexual function, only three (3.49%) stated that sexual dysfunctions had influenced their decision, whereas in the sexual dysfunction group, 27 (31.4%) confirmed this experience. This difference is statistically significant, Fisher test, P =0.0033. The more severe the sexual dysfunction, the higher the percentage of those who stated that sexual dysfunction influenced their decision to start taking drugs. This trend is statistically significant, P <0.0025. About 50% of the entire sample admitted they had used drugs to improve sexual performance. Conclusions Users of illicit drugs report a high prevalence of sexual disorders prior to FDU. A large percentage claimed that sexual dysfunction influenced their decision to start taking drugs. The higher the severity of the sexual disorders, the higher the percentage of those claiming that sexual dysfunction had influenced their decision. In our opinion, these data highlight a possible new strategy in the primary prevention of substance abuse in which sexual education and early treatment of sexual disorders, among adolescents, may prevent them from FDU.

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Section: Figurementioning

confidence: 63%

“…For several years, our research group [6–9] has adopted a different approach to the sex and drugs link, proposing the opposite concept to that generally considered valid.…”

Section: Introductionmentioning

confidence: 99%

Sexual Dysfunction Prior to First Drug Use Among Former Drug Addicts and Its Possible Causal Meaning on Drug Addiction: Preliminary Results

Pera

Carderi

Marianantoni

et al. 2008

The Journal of Sexual Medicine

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Sexual Dysfunction and Psychopathological Variables Among Tramadol Abusers: An Egyptian Perspective

Mobasher¹,

Hassanin

Elsayed³

et al. 2020

Addictive Disorders &Amp; Their Treatment

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Objectives: The relationship between tramadol and sexual function seems to be controversial, men with premature ejaculation may benefit from taking tramadol off-label. Yet, these patients are rather sensitive to develop other sexual dysfunctions. To date, rather a limited number of studies investigated this issue. In addition, psychological concerns related to sexual functions in these patients had not enough attention. In this paper we present a new approach which will investigate these concerns Materials and Methods: Sixty subjects (30 tramadol-dependent men and 30 matched controls). Patients were assessed by the Mini International Neuropsychiatry Interview (MINI) is to assesses the presence of The Diagnostic and Statistical Manual of Mental Disorder, 4th edition disorders, the Addiction Severity Index (ASI), the International Index of Erectile Function (IIEF), and the Sexuality Scale. Results: Tramadol patients were found to have significantly decreased different sexual functions in comparison with controls. Sexual depression scores were significantly higher in tramadol patients compared with controls (P=0.020); while sexual-esteem and sexual preoccupation scores were significantly lower in tramadol patients compared with matched controls (P=0.000 and 0.046). In the patient group, the dose of tramadol used per day showed significant negative correlation with erectile function (P=0.04), orgasmic function (P=0.03), and sexual esteem (P=0.04); while the duration of tramadol dependence showed significant negative correlation with erectile function (P=0.04), intercourse satisfaction (P=0.01), overall satisfaction (P=0.00), and significant positive correlation with sexual preoccupation. Conclusions: Tramadol patients indeed suffer from different sexual, emotional, occupational dysfunctions, and sexually related psychopathological aspects.

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To What Extent Is Heroin Used to Relieve Premature Ejaculation and Other Sexual Disorders?

Cited by 2 publications

References 0 publications

Sexual Dysfunction Prior to First Drug Use Among Former Drug Addicts and Its Possible Causal Meaning on Drug Addiction: Preliminary Results

Sexual Dysfunction Prior to First Drug Use Among Former Drug Addicts and Its Possible Causal Meaning on Drug Addiction: Preliminary Results

Sexual Dysfunction and Psychopathological Variables Among Tramadol Abusers: An Egyptian Perspective

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