Tobacco-alcohol optic neuropathy. Is complete recovery possible?

Joseph, Sobha; Al-Ali, Sahar; Tripathi, Ajay

doi:10.4103/0974-620x.127948

Cited by 3 publications

(2 citation statements)

References 5 publications

(5 reference statements)

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“…Few studies have shown that administration of noncyanide-containing vitamin B12 produced a rapid improvement in visual acuity even in those patients who continued smoking. [12] There is evidence that in tobacco amblyopia primary lesion is a degeneration of the ganglion cell layer of retina with secondary atrophy of nerve fiber layer of retina and the papillomacular bundle of the optic nerve. [12,13] Apparently, tobacco amblyopia is due to disturbance in the distribution of thiocyanate in body fluids; it is in fact a form of cyanide poisoning as confirmed by its response to treatment with intramuscular hydroxycobalamine even with continued consumption of tobacco.…”

Section: Discussionmentioning

confidence: 99%

Study of visual field in healthy chronic smokers

Jain¹,

Nagarsheth²,

Desai³

2015

Natl J Physiol Pharm Pharmacol

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Background: Visual disturbances caused by smoking have been studied extensively though the pathogenesis is poorly understood. The significance to diagnose visual field disturbances because of smoking is that prognosis for return of vision is always good if the consumption of tobacco is restrained timely. Aims & Objective: To study visual field in healthy smokers. Materials and Methods: In this study, subjects from the outpatient clinic were selected randomly: 30 healthy smokers and 30 nonsmokers. These subjects were divided into two groups: test (smokers) and control (nonsmokers). Ocular examination of all the subjects was done including intraocular pressure measurement and fundus examination. Further, visual field analysis was carried out using an automated perimeter (M700; Medmont International). Then, interpretation of visual field was done along with assessment of visual field defects. Values obtained were analyzed using Z-test and unpaired Student's t-test. p-Value less than 0.05 was considered to be statistically significant. Results: Average deviation (AD) and patterned deviation (PD) were found to be significantly high in smokers as compared to nonsmokers (p < 0.001). It was also observed that AD and PD were significantly high if the smoking load (average number of cigarettes multiplied by average duration of smoking) is more than 50,000 (p < 0.005 and p < 0.02, respectively). In smokers, retinal sensitivity was found to decrease and the presence of localized scotomas was observed, but the central vision was found to be preserved. Conclusion: This study is important in diagnosing visual field defects in tobacco amblyopia to stop nicotine toxicity in time with early intervention, thereby preventing further damage to the optic nerve.

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Section: Discussionmentioning

confidence: 99%

Study of visual field in healthy chronic smokers

Jain¹,

Nagarsheth²,

Desai³

2015

Natl J Physiol Pharm Pharmacol

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“…[18] The management includes reduction or cessation of alcohol intake, and vitamin B12 and folate supplementation. [75]…”

Section: Alcohol-related Optic Neuropathymentioning

confidence: 99%

Alcohol and the Eye

Karimi

Arabi

Shahraki

2021

JOVR

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In this article, we present a review of ocular conditions related to alcohol consumption. A search of the literature published from 1952 to March 2020 was performed. The titles and abstracts were screened and the eligible studies were selected. PubMed, ISI Web of Knowledge database, Scopus, Embase, and the Cochrane Library were searched. We categorized the relationship between alcohol intake and ocular conditions by the type of ocular exposure to alcohol. Accordingly, ocular findings following acute alcohol intoxication, optic neuropathy following methanol toxicity, congenital conditions related to maternal alcohol consumption, and ocular disease related to chronic alcoholism are discussed. The main feature of alcohol intoxication in the eye is abnormal eye movement. Acute optic neuropathy secondary to methyl alcohol consumption is a serious ocular disease with permanent vision loss or scotoma. Prenatal exposure to ethanol may end in fetal alcohol spectrum disease, where ocular findings are a constant component. The association between chronic alcohol consumption and increased risks of cataract, age-related macular degeneration, diabetic retinopathy, different types of optic neuropathy, impairment of visual quality, retinal vascular disease, and ocular surface disease has also been reported. Along with detrimental medical and social effects, the role of alcohol consumption in different ocular conditions should be considered, as alcohol-induced visual disturbances may contribute to the heavy burden of alcohol abuse on the healthcare system and overall quality of life.

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Alcohol intoxication and ophthalmological pathology

Нагорнова

Seleznev

Brezhnev

et al. 2023

jour

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Alcohol-containing drinks are widespread throughout the world, and alcohol ingestion is a part of the culture of diff erent peoples and an integral part of their daily diet. At the same time, alcohol abuse leads to adverse consequences such as home accidents, poisoning and various somatic diseases. However, there is also an opinion that alcohol can have a benefi cial eff ect on the body by its vasodilation and blood circulation improvement. The review analyzes the data of works that studied the positive and negative eff ects of alcohol on the visual organ, while highlighting the problems of acute intoxication and chronic alcohol ingestion.

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Tobacco-alcohol optic neuropathy. Is complete recovery possible?

Cited by 3 publications

References 5 publications

Study of visual field in healthy chronic smokers

Study of visual field in healthy chronic smokers

Alcohol and the Eye

Alcohol intoxication and ophthalmological pathology

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