Tobacco Use and Cryptogenic Stroke in Young Adults

Jaffre, Aude; Ruidavets, Jean Bernard; Nasr, Nathalie; Guidolin, Brigitte; Ferrières, Jean; Larrue, Vincent

doi:10.1016/j.jstrokecerebrovasdis.2015.07.022

Cited by 11 publications

(7 citation statements)

References 32 publications

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“…Potential mechanisms of stroke associated with PFO include paradoxical embolism and, in patients with an atrial septal aneurysm, atrial dysfunction . Reports of thrombus associated with NOCA in young adults with stroke indicate that NOCA may cause stroke through activation of thrombogenesis, especially in smokers . Alternatively, however, NOCA may only be a marker of diffuse atherosclerosis and not the culprit lesion.…”

Section: Discussionmentioning

confidence: 99%

Non‐obstructive carotid atherosclerosis and patent foramen ovale in young adults with cryptogenic stroke

Jaffre

Guidolin

Ruidavets

et al. 2017

Euro J of Neurology

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Section: Discussionmentioning

confidence: 99%

Non‐obstructive carotid atherosclerosis and patent foramen ovale in young adults with cryptogenic stroke

Jaffre

Guidolin

Ruidavets

et al. 2017

Euro J of Neurology

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“…In a recent study, the authors demonstrated a strong relation between tobacco use and cryptogenic stroke in young adults. 12 A possible explanation for this could be an increased risk of AF for current smokers in a dose dependent manner. 13 If the isolated vascular risk factors were not so different, except for age and smoking habit, the score values of CHADS 2 and CHA 2 DS 2 VASc revealed a more benign profile of ESUS when compared to AF.…”

Section: Discussionmentioning

confidence: 99%

Embolic Stroke of Undetermined Source (ESUS) and Stroke in Atrial Fibrillation Patients: not so Different after all?

Scavasine¹,

Ribas²,

Costa³

et al. 2021

International Journal of Cardiovascular Sciences

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Embolic Stroke of Undetermined Source (ESUS) is a non-lacunar infarct without proximal occlusive atherosclerosis or major-risk cardioembolic sources. Recent studies have demonstrated a high variability (ranging from 10-39%) in the proportion of ESUS patients, who are subsequently diagnosed with atrial fibrillation (AF) in a long-term follow-up. This result suggests that some groups of ESUS patients can present AF as underlying cause of stroke. [2][3][4][5] Approximately one-third of the patients who met the inclusion criteria for ESUS trials presented AF in continuous heart rhythm monitoring for up to three years. A higher AF prevalence was also observed with an increasing number of CHADS 2 risk factors. 6

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“…107 The use of tobacco may be linked to cryptogenic stroke in young adults. 108 The remainder of cryptogenic strokes are caused by patent foramen ovale or hypercoagulable states. 101 In patients who are found to have patent foramen ovale, patent foramen ovale-occluding devices may decrease the risk of recurrent stroke compared with medical therapy in patients with cryptogenic stroke.…”

Section: Cryptogenic Strokementioning

confidence: 99%

Emergency management of stroke in the era of mechanical thrombectomy

Brandler

Baksh

2019

Clin Exp Emerg Med

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Emergency management of stroke has been directed at the delivery of recombinant tissue plasminogen activator (tPA) in a timely fashion. Because of the many limitations attached to the delivery of tPA and the perceived benefits accrued to tPA, its use has been limited. Mechanical thrombectomy, a far superior therapy for the largest and most disabling strokes, large vessel occlusions (LVOs), has changed the way acute strokes are managed. Aside from the rush to deliver tPA, there is now a need to identify LVO and refer those patients with LVO to physicians and facilities capable of delivering urgent thrombectomy. Other parts of emergency department management of stroke are directed at identifying and mitigating risk factors for future strokes and at preventing further damage from occurring. We review here the most recent literature supporting these advances in stroke care and present a framework for understanding the role that emergency physicians play in acute stroke care.

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Tobacco Use and Cryptogenic Stroke in Young Adults

Cited by 11 publications

References 32 publications

Non‐obstructive carotid atherosclerosis and patent foramen ovale in young adults with cryptogenic stroke

Non‐obstructive carotid atherosclerosis and patent foramen ovale in young adults with cryptogenic stroke

Embolic Stroke of Undetermined Source (ESUS) and Stroke in Atrial Fibrillation Patients: not so Different after all?

Emergency management of stroke in the era of mechanical thrombectomy

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