2020
DOI: 10.4067/s0034-98872020000701039
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Tofacitinib en el tratamiento de la colitis ulcerosa: casos clínicos

Abstract: Tofacitinib for the treatment of ulcerative colitis. Report of two cases Biological therapy dramatically changed the management of Ulcerative Colitis (UC). However, a significant number of these patients fail to respond or have secondary loss of response to this strategy. In this clinical situation, the options include intensification of anti-TNF therapy, the use of a second anti-TNF or being switched to another drug class. Among the later, tofacitinib, an oral small molecule directed against the JAK/STAT path… Show more

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