Tolerance and Biocompatibility of Micronized Black Pigment for Keratopigmentation Simulated Pupil Reconstruction

Abstract

Central keratopigmentation presented good cosmetic appearance without adverse effects. These results suggest the adequacy of mineral micronized pigments for successful keratopigmentation. The hen animal model is a suitable model for assaying the biocompatibility and tolerance of micronized pigments in central keratopigmentation.

Femtosecond-assisted keratopigmentation for functional and cosmetic restoration in essential iris atrophy

“…1,5 To our knowledge, this is the first report of the successful applicability of femtosecond-assisted KTP in a patient with this iris anatomical and functional defect.…”

“…In our case, the femtosecond-assisted KTP was very effective and could solve the patient's symptoms and provide an excellent cosmetic result. The use of new micronized mineral pigments with an adequate toxicology study 1,5 is an essential step in the modern development of KTP. Our experience using this pigment has demonstrated it to be safe during a 2-year follow-up.…”

“…1,2 The therapeutic effect has been shown in patients with symptomatic glare associated with iris loss, atrophy, or trauma; in cases of disabling light scattering and photophobia in posttraumatic aniridia or iris coloboma [3][4][5] ; and even in the treatment of incapacitating diplopia. 6 Iris nevus (Cogan-Reese) syndrome, Chandler syndrome, and essential iris atrophy are 3 clinical variations of the iridocorneal endothelial syndrome (ICE).…”

Shave Excision With Keratopigmentation for Limbal Dermoid

“…Dyes can be in the form of powder, paste, colloid, or solution. [9][10][11][12][13] Metallic salts, India ink, commercially available drawing ink, tattooing ink for dermatological use, and organic and vegetable dyes have been used for corneal tattooing. Technique of application includes anterior stromal puncture, surface tattooing after epithelial debridement, and stromal tattooing after creating a microkeratome or femtosecond-based lap.…”

Femtosecond-Assisted Keratopigmentation Double Tunnel Technique in the Management of a Case of Urrets-Zavalia Syndrome

“…The use of new micronized mineral pigments with an adequate toxicology study 1,13 is an essential step in the modern development of KTP. Our experience using this pigment in an experimental animal model and in patients has demonstrated it to be safe during a 2-year follow-up.…”