“…3 A study in the south of Iran on 150 patients with colorectal cancer and 150 control people showed a significant relationship between the TLR2 Arg753Gln polymorphism and colorectal cancer [32]. A metaanalysis study revealed that rs5743708 polymorphism was related to hepatocellular carcinoma (HCC) and decreased survival of patients with stages III and IV of advanced colon cancer [33]. Therefore, regardless of whether the rs5743708 polymorphism has a positive or negative effect on cancer, most studies have pointed out the influential role of this polymorphism in cancer.…”