Tolosa-Hunt syndrome: MR imaging features in 15 patients with 20 episodes of painful ophthalmoplegia

Schuknecht, B.; Sturm, Veit; Huisman, Thierry A. G. M.; Landau, Klara

doi:10.1016/j.ejrad.2007.11.034

Cited by 78 publications

(60 citation statements)

References 26 publications

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“…The granulomatous lesion seems isointense in T1 sequences and iso-hypointense in T2 sequences and shows significant contrast involvement after the intravenous injection of the contrast material, but MRI might also be normal in many patients who have the clinical characteristics of THS (18,19,20). We observed in our patients that if the MRI was normal or if the lesions in the MRI were small, recurrence was rare.…”

Section: Discussionmentioning

confidence: 99%

“…If lacrimal gland involvement is not significant in MRI, it is possible to misdiagnose the condition as THS. Also, THS may be a variant of the orbital pseudotumor, and these two diseases may be thought of as the different presentations of the same pathology (24). Periorbital pain due to THS responds quickly and dramatically to corticosteroids, but it should not be forgotten that a good response to corticosteroids may also be observed in lymphoma, vasculitis, and paracellar epidermoid tumors (6,18).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Tolosa-Hunt Syndrome - Cranial Neuroimaging Findings

Akpınar¹,

Özbenli²,

Doğru³

et al. 2017

Arch Neuropsychiatr

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Tolosa-Hunt Syndrome - Cranial Neuroimaging Findings

Akpınar¹,

Özbenli²,

Doğru³

et al. 2017

Arch Neuropsychiatr

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“…The etiology remains unknown; however, the pathogenesis has been proven to involve granulomatous inflammation in the cavernous sinus, superior orbital fissure and/or orbit, which is often displayed on magnetic resonance imaging (MRI) (1)(2)(3). In this report, we describe the case of an adult woman with THS characteristically associated with cytomegalovirus (CMV) infection.…”

Section: Introductionmentioning

confidence: 97%

Tolosa-Hunt Syndrome Associated with Cytomegalovirus Infection

et al. 2013

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We herein present the case of a 38-year-old woman with left-sided oculomotor paralysis with ocular pain that developed after a respiratory infection. Her serum was positive for IgM against GM2 and GalNAc-GD1a gangliosides and cytomegalovirus. Thin-slice magnetic resonance imaging revealed enhanced abnormal tissue located primarily in the superolateral part of the left-sided cavernous sinus, which corticosteroids subsequently obscured with immediate resolution of the patient's ocular symptoms. These clinical features were consistent with those of Tolosa-Hunt syndrome (THS). Our findings in the present patient suggest that cytomegalovirus may provoke granuloma formation in the cavernous sinus, as reported in other various organs, thereby leading to the development of THS.

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“…Our patient's MRI was unremarkable. Although most cases of suspected THS syndrome have enlargement of the cavernous sinus on MRI, some cases were found to show changes only on repeat examination 8,9 . Kobor et al found that of 38 reviewed cases of THS reporting imaging results, eight initially had unremarkable MRI findings, three of which later had positive findings on repeat imaging 8 .…”

Section: Commentsmentioning

confidence: 99%