Toluene polymer as a new stationary phase in reversed-phase column liquid chromatography

Nasuto, R.; Kwietniewski, L.

doi:10.1007/bf02261230

Cited by 7 publications

(6 citation statements)

References 25 publications

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“…This can facilitate the separation of solutes with similar structures. [24][25][26] Their differential selectivity has been attributed mainly to π-π interactions that augment the fundamentally hydrophobic process that is responsible for retention in RPLC. [27][28][29] A great deal of research using LSERs has been carried out to better understand the intermolecular processes in RPLC stationary phases.…”

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confidence: 99%

“…The utility of aromatic bonded phases is related to their differential selectivity, mainly for aromatic compounds, compared to alkyl-bonded silicas. This can facilitate the separation of solutes with similar structures. − Their differential selectivity has been attributed mainly to π−π interactions that augment the fundamentally hydrophobic process that is responsible for retention in RPLC. − …”

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confidence: 99%

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Comparative Study of Hydrocarbon, Fluorocarbon, and Aromatic Bonded RP-HPLC Stationary Phases by Linear Solvation Energy Relationships

et al. 1999

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The retention properties of eight alkyl, aromatic and fluorinated reversed-HPLC bonded phases were characterized through the use of Linear Solvation Energy Relationships (LSERs). The stationary phases were investigated in a series of methanol-water mobile phases. LSER results show that solute molecular size under all conditions and hydrogen bond acceptor basicity are the two dominant retention controlling factors and that these two factors are linearly correlated when either different stationary phases at a fixed mobile phase composition or different mobile phase compositions at a fixed stationary phase are considered.The large variation in the dependence of retention on solute molecular volume as only the stationary phase is changed indicate that the dispersive interactions between nonpolar solutes and the stationary phase are quite significant relative to the energy of the mobile phase cavity formation process.Principal Component Analysis (PCA) results indicate that one PCA factor is required to explain the data when stationary phases of the same chemical nature (alkyl, aromatic and fluoroalkyl phases) are individually considered. However, three PCA factors are not quite sufficient to explain the whole data set for the three classes of stationary phases. In spite of this, the average standard deviation obtained by the use of these principal components factors are significantly smaller than the average standard deviation obtained by the LSER approach. In addition, selectivities predicted through the LSER equation are not in complete agreement with experimental results.These results show that the LSER model does not properly account for all molecular interactions involved in RP-HPLC. The failure could reside in the V 2 solute parameter used to account for both dispersive and cohesive interactions since "shape selectivity" predictions for a pair of structural isomers are very bad.

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Comparative Study of Hydrocarbon, Fluorocarbon, and Aromatic Bonded RP-HPLC Stationary Phases by Linear Solvation Energy Relationships

et al. 1999

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“…The process of bonding cyclohexane radicals to the silica gel surface was carried out via two steps: (i) surface activation involving the electrophilic reaction of SiCl 4 vapour using the method described previously (Nasuto and Dudzi ska 1985;Buszewski et al 1981Buszewski et al , 1983:…”

Section: Synthesis Of Adsorbents With Chemically Bonded Stationary Phmentioning

confidence: 99%

“…Thus, over 80% of methods used for the analysis of chemical compounds are chromatographic in origin and 90% of these use adsorbents with chemically or adhesively bonded stationary phases (Werner and Halasz 1980;Suprynowicz 1986). The principal aim in the synthesis of adsorbents with bonded phases is the optimization of the molecular interactions between the components in the separated mixtures and the phases in the chromatographic system (Lisitchkin 1986;Gruskha 1974;Unger 1979Unger , 1990Laskorin 1977;Rehàk and Smolkova 1976;Engelhardt and Ahr 1981;Felix et al 1992;Grizzle and Thompson 1982). Optimization of the interactions in a chromatographic system is obtained not only as a result of the proper choice of stationary phase modifiers but also as a result of changes in the concentration of modifier bonded with the stationary phase.…”

Section: Introductionmentioning

confidence: 99%

“…Only a limited number of papers have been devoted to studies of the influence of the change in concentration of the stationary phase modifier upon the retention of chromatographed chemical compounds (Motolla and Steinmetz 1992;Kirkland 1975;Tanaka et al 1984;Nasuto and Kwietniewski 1990;Dhanesar and Poole 1983;Unger et al 1973Unger et al , 1976Kikta and Grushka 1976).…”

Section: Introductionmentioning

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The Influence of the Concentration of Cyclohexane Radicals Bonded with an Si100 Silica Gel Surface upon the Retention of Some Hydrocarbons in Gas Chromatography

Nasuto

2000

Adsorption Science & Technology

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Four adsorbents based on silica gel Si100 with chemically bonded cyclohexane have been prepared as stationary phases for gas chromatography. The concentrations of cyclohexane radicals thus bonded with the silica gel surface were 1.35, 3.35, 4.17 and 6.02 μmol/m2, respectively. Separation of aliphatic (C6–C12), aromatic (benzene, toluene and m-xylene) and some polar organic compounds (chloroform, ethylene chloride, chlorobenzene, p-chlorotoluene and ethyl benzene) by gas chromatography using columns packed with the prepared adsorbents was studied. It was concluded that the retention of some compounds was increased on the column packed with an adsorbent of 1.35 μmol/m2 concentration relative to that measured on the column packed with the unmodified silica gel. On columns packed with adsorbents with a higher bonded phase concentration than 1.35 μmol/m2, the retention times of all the compounds studied chromatographically decreased with an increase in the bonded phase concentration.

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Characterising the chemical interactions that occur on polyaniline with inverse thin layer chromatography

Teasdale

Wallace

1994

Polymer International

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Inverse thin layer chromatography is used to characterise the chemical interactions that occur on polyaniline that has been electrochemically deposited on to a support. Amino acids are used as the molecular probe species by which the retention behaviour can be related to particular chemical interactions. The mobile phase is also varied, with respect to its polarity and pH, in order to add a further dimension to the qualitative information that is obtained. Anion exchange interactions are found to be the dominant interaction type. However, the behaviour seems to be different to that which occurs on conventional anion exchange materials. The behaviour was dependent upon the number of negative sites and also their spatial arrangement. A configurational‐selective ionic interaction with the polaron lattice of the polyaniline is proposed. The response of the anion exchange behaviour to a change of pH suggested that protonated sites remained within the polymer, even at high pH values (c 9).

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Toluene polymer as a new stationary phase in reversed-phase column liquid chromatography

Cited by 7 publications

References 25 publications

Comparative Study of Hydrocarbon, Fluorocarbon, and Aromatic Bonded RP-HPLC Stationary Phases by Linear Solvation Energy Relationships

Comparative Study of Hydrocarbon, Fluorocarbon, and Aromatic Bonded RP-HPLC Stationary Phases by Linear Solvation Energy Relationships

The Influence of the Concentration of Cyclohexane Radicals Bonded with an Si100 Silica Gel Surface upon the Retention of Some Hydrocarbons in Gas Chromatography

Characterising the chemical interactions that occur on polyaniline with inverse thin layer chromatography

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