One of the main factors that assist to increase the growth of any country is Agriculture. The detection of diseases from plant leaf images is one of the most important fields of agricultural research. To identify disease factors, this field requires a reliable prediction approach. Data Mining (DM) is the process of analyzing data from different aspects and summarizing it into valuable information. It helps users to categorize and identify relationships between data from various dimensions. As there are many plants on the farm, detecting and classifying the diseases of each plant on the farm is extremely difficult for the human eye. And diagnosing each plant is very critical since these diseases may spread. DM classification is an important method that has a wide range of applications. It classifies each item in a set of data into one of a set of predefined classes. In this paper, a comparison of different DM classification methods such as Naive Bayes, Decision trees, SVM, and Random Forest algorithms has been illustrated by using of Weka Tool.