Tonsil size as a predictor of cardiac complications in children with sleep‐disordered breathing

Granzotto, Eduardo Homrich; Aquino, Flávio; Flores, José Antônio Monteiro; Neto, José Faibes Lubianca

doi:10.1002/lary.20870

Cited by 21 publications

(17 citation statements)

References 31 publications

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“…Interestingly, adenoid size significantly predicted early airway complications. This aligns with a recent study that showed that tonsil size predicts cardiac complications in children with sleepdisordered breathing [13].…”

Section: Discussionsupporting

confidence: 87%

Predicting complications after adenotonsillectomy in children 3 years old and younger

McCormick

Sheyn

Haupert

et al. 2011

International Journal of Pediatric Otorhinolaryngology

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Section: Discussionsupporting

confidence: 87%

Predicting complications after adenotonsillectomy in children 3 years old and younger

McCormick

Sheyn

Haupert

et al. 2011

International Journal of Pediatric Otorhinolaryngology

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“…We also added measurements of upper airway sizes as additional variables. Although the size of the upper airway predisposes for sleep‐disordered breathing, it is a potential confounding factor for hypertension as well 25. To our knowledge, upper airway sizes are potential confounders often not included in previous large studies on the association of sleep apnea and hypertension.…”

Section: Discussionmentioning

confidence: 99%

The association between sleep apnea and young adults with hypertension

Asha'ari¹,

Hasmoni²,

Rahman

et al. 2012

The Laryngoscope

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Objectives/Hypothesis:To study the association between sleep apnea and hypertension in a younger age group than previously studied, adding upper airway sizes at endoscopy as important compounding variables not often included in the past.Study Design:Case control.Methods:We analyzed data on sleep‐disordered breathing (based on polysomnography tests), body mass index (BMI), neck circumference, upper airway endoscopy sizes, and habitus and health history in 120 hypertensive and 120 nonhypertensive participants in a clinic‐based setting. Independent t test, χ2, multivariate analysis, and binary logistic regression models were used for case‐control comparison.Results:The mean age of the participants was 27 years; 67.5% were male. The incidence and severity of sleep apnea were significantly higher in the hypertensive than the control subjects. Persons with hypertension had an OR of 2.7 times of having comorbid sleep apnea than patients without hypertension (95% confidence interval [CI] 1.2‐6.1). Persons with sleep apnea (AHI [apnea‐hypopnea index] ≥5) had an OR of 2.76 (95% CI 1.57‐4.86), and persons with severe sleep apnea (AHI ≥30) had an OR 7.94 (95% CI 4.21‐15.33) for having hypertension than did persons without sleep apnea. Although adjustments for the compounding factors, particularly BMI, decreased the OR to a large degree, subjects with severe sleep apnea were still 72% more likely to have hypertension than subjects without sleep apnea.Conclusions:Sleep apnea is related to hypertension in young adults aged 18 to 40 years. The association was more pronounced with the increasing severity of sleep apnea. Screening for sleep apnea should be considered in young adults with hypertension.

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“…Other disorders have also been described in association with obstructive apnea: enuresis, 10 night sweats, daytime sleepiness, behavior disorders, d e v e l o p m e n t a l d e l a y ( r e l a t e d t o h e i g h t and weight growth and learning), 11 arterial hypertension 12 and, in extreme cases, pulmonary hypertension and right heart failure. 13 Although it is a common sign, it is not normal for a child to snore. Snoring occurs during childhood in 6-20% of children, depending on…”

Section: Discussionmentioning

confidence: 99%

Assessment of quality of life before and after an adenotonsillectomy among children with hypertrophic tonsils and/or adenoids

2015

Arch Argent Pediat

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Introduction.Adenotonsillectomy is the most common surgical procedure in otolaryngology. The main indication for this procedure is upper airway obstruction associated with hypertrophic tonsils and/or adenoids. Objectives. To describe the differences in quality of life before and after an adenoidectomy and/ or tonsillectomy and compare it with that of healthy children. Population and Methods. All children aged 1 to 17 years old hospitalized for an elective surgery between July 2012 and April 2014 were enrolled. They were compared to a control group of children in the same age range. The survey used was validated in Spanish (OSA-18) and has been especially designed to establish a relationship between obstructive sleep apnea and quality of life in pediatrics. Results. Eighty-five surgery patients and 100 healthy control children were assessed. The impact on quality of life was mild in 37.6% of children, moderate in 32.9%, and severe in 29.4%, while it was mild for 96% of the control group. The average ± SD of the total pre-surgery score was 67.5 ± 20.3 (95% confidence interval [CI]: 63.13-71.88). The average post-surgery scores were 37.9 ± 21.4 (95% CI: 33.24-42.48) and ) at 3 and 6 months, respectively (p < 0.001). The average score for the control group was 31.2 ± 13.2 (95% CI: 28.6-33.8) and was significantly different from the post-surgery groups (p = 0.03). Conclusions. Quality of life was reduced in children with a surgical indication for symptomatic adenotonsillar hypertrophy, while it was significantly improved after the surgery.

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Tonsil size as a predictor of cardiac complications in children with sleep‐disordered breathing

Cited by 21 publications

References 31 publications

Predicting complications after adenotonsillectomy in children 3 years old and younger

Predicting complications after adenotonsillectomy in children 3 years old and younger

The association between sleep apnea and young adults with hypertension

Assessment of quality of life before and after an adenotonsillectomy among children with hypertrophic tonsils and/or adenoids

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