Tonsillar metastasis from a renal cell carcinoma presenting as a quinsy

Green, K. M. J.; Pantelides, E.; Carpentier, J.-P.

doi:10.1017/s0022215100137375

Cited by 17 publications

(9 citation statements)

References 7 publications

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“…In agreement with other researchers, the possibility of PTA as an independent risk factor for tonsillar malignancy was questioned [1,3,10]. A literature search revealed several case reports on tonsillar malignancy presenting as PTA, which supported the concept that PTA may be associated with tonsillar malignancy [5][6][7][8][9][10][12][13][14]. Thus, clarification of whether PTA should be added to the list of risk factors indicating histological examination is warranted.…”

Section: Introductionsupporting

confidence: 69%

“…In seven cases (54 %), malignancy was unsuspected. If the previously mentioned risk factors for tonsillar malignancy had been applied, some of these malignancies would have been suspected; the patient described by Green et al (Table 3, case number 3) had a history of cancer and the second case reported by Holmes et al (Table 3, case number 6) was immunocompromised due to HIV [6,7]. Both conditions are included in the list of risk factors for tonsillar malignancy indicating histological examination.…”

Section: Discussionmentioning

confidence: 99%

“…He had a 3-day history of increasing dysphagia and unilateral throat pain. The clinical impression was of a PTA and malignancy was not suspected [6]. The second case published by Holmes et al [7].…”

Section: Pta Patients With Unsuspected Tonsillar Malignancymentioning

confidence: 99%

“…Unsuspected tonsillar malignancy, diagnosed by coincidence because of routine histological examination, is infrequently found in patients presenting with peritonsillar abscess (PTA) [3,[5][6][7][8][9][10][11]. In a recent review, unsuspected tonsillar malignancy was found in three out of 6,434 adult patients (prevalence 0.05 %) because of routine histological examination of the tonsils.…”

Section: Introductionmentioning

confidence: 99%

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Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

Rokkjær

Klug

2014

Eur Arch Otorhinolaryngol

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Unsuspected tonsillar malignancy in routine tonsillectomy specimens is rare. A potentially increased risk of unsuspected tonsillar malignancy in adult patients presenting with peritonsillar abscess (PTA) was noted in a recent review. Furthermore, a literature search revealed several case reports concerning tonsillar malignancy presenting as PTA. Thus, the aim of the current study was to explore the prevalence of tonsillar malignancy in adult patients with PTA. A retrospective review of all adult patients undergoing tonsillectomy due to PTA from January 2001 to December 2012 at the Ear-Nose-Throat Department was performed. In 275 consecutive adult patients with PTA (median age 40 years, range 30-89 years), we identified one patient with unsuspected tonsillar malignancy (prevalence 0.3 %); a 40-year-old, previously healthy, male was diagnosed with acute myeloid leukaemia. Reviewing the literature, we identified 13 cases of tonsillar malignancy presenting as PTA (median age 49 years, range 2-66 years). Our data represents the only series of histological examined tonsillectomy specimens from PTA patients reported in the literature. We identified one case of unsuspected tonsillar malignancy in this relatively small series. We find it important to stress, that we had no knowledge of this patient before designing the study. Hence, the prevalence of 0.3 % is unbiased in this respect. More, and preferably, larger studies are needed to determine the prevalence with greater certainty. At present, no definitive conclusions can be made, but clinicians should be aware that PTA infrequently masquerade tonsillar malignancy.

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Section: Introductionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Pta Patients With Unsuspected Tonsillar Malignancymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

Rokkjær

Klug

2014

Eur Arch Otorhinolaryngol

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“…Older patients presenting with peritonsillar abscesses may require further assessment to detect OPC. [5][6][7] It is impossible to say if patients' prognoses were affected by delayed diagnosis. However, earlier-stage OPC has a better prognosis than advanced stage and the nonresolving nature of the symptoms in these patients were suggestive of malignancy.…”

Section: Methodsmentioning

confidence: 99%