Tooth extraction in patients on chronic anticoagulant treatment – preliminary results of a clinical prospective study

Abstract

Patients under anticoagulant treatment which needs dental extractions have a significant high risk of postoperative bleeding, in consequence they need either hospitalization or ambulatory postextractional monitoring. The objective of this study was while using Surgicel® as a socket local hemostat for extractions at patients under anticoagulants to prove his efficacy during a clinical prospective experimental study. We followed three groups of patients under anticoagulant treatment with single or multiple dental extractions: one group under oral anticoagulants (warfarin) and socket meshing with Surgicel®, one group under i.v. anticoagulants (heparin) and one control group under antithrombotics. Many parameters were observed and studied with special focus on postextractional hemorrhage. Results were statistically analyzed and they were compared with the latest findings on international literature. The study conclusions suggest using Surgicel® as viable intraalveolar hemostat which can reduce many postoperative bleeding accidents and avoid thrombotic risks associated with suppression of oral anticoagulant or heparin treatment.