Tooth loss and osteoporosis: to assess the association between osteoporosis status and tooth number

Darcey, James; Horner, Keith; Walsh, Tanya; Southern, H. N.; Marjanovic, Elizabeth; Devlin, Hugh

doi:10.1038/sj.bdj.2013.165

Cited by 49 publications

(50 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Darcy et al [19] & Passos et al [20] indicate the relationship between osteoporosis and tooth loss, which does not match with our studies. In Lundstram's [21] study also examined the relationship between osteoporosis and the number of missing teeth and the results showed no significant difference between osteoporosis and the number of missing teeth and results also match with the study.…”

Section: Discussioncontrasting

confidence: 97%

Assessment the Relationship between Osteoporosis with Tooth Loss and Dry Mouth in Women with Osteoporosis

A¹

2016

MOJPH

View full text Add to dashboard Cite

Introduction: Osteoporosis is the most common metabolic bone disease and protests include decreased bone mineral and underlying tissue. Due to the prevalence of osteoporosis, especially in women and its complications, a study to evaluate the association of osteoporosis with tooth loss and oral dryness feeling in women with osteoporosis was designed. Materials and Methods:This cross sectional study was performed on 170 women referred to the center of bone densitometry of Fasa city. Data were collected using a valid questionnaire including standard questionnaire of xerostomia and demographic variables, also a clinical examination was carried out for determine the number of missing teeth. Then, the data were entered into the SPSS 19 and were analyzed. P<0.05 was considered as statistically significant. Results:The findings of this study showed that there was significant relationship between osteoporosis and oral dryness feeling (p<0.001). But no significant difference was found between the two groups regarding average number of teeth missing (p=0/09). However, significant difference was found between age and number of missing teeth (p=0/02). Conclusion:The results showed that osteoporosis cannot be considered risk factors for tooth loss. But there is a positive relationship between osteoporosis and oral dryness feeling in women.

show abstract

Section: Discussioncontrasting

confidence: 97%

Assessment the Relationship between Osteoporosis with Tooth Loss and Dry Mouth in Women with Osteoporosis

A¹

2016

MOJPH

View full text Add to dashboard Cite

show abstract

“…A previous study reported a significant relationship between a decreased number of remaining molar teeth and osteoporosis, and concluded that osteoporotic patients are more likely to lose teeth. 21 Our study failed to demonstrate a statistical correlation between tooth loss and decreased BMD.…”

Section: Discussioncontrasting

confidence: 70%

Identifying dental panoramic radiograph features for the screening of low bone mass in postmenopausal women

Geary

Selvi

Chuang

et al. 2015

International Journal of Oral and Maxillofacial Surgery

View full text Add to dashboard Cite

“…Forty-eight 3-month-old female Sprague-Dawley rats were randomly divided into two groups: an ovariectomized (OVX) group (n = 24) and Sham-operated (SHAM) group (n = 24). Six rats were randomly sacrificed from both groups at time points 8,12,16, and 20 weeks. The samples from tibia and maxilla were collected for micro computed tomography (mCT) and histological analysis.…”

mentioning

confidence: 99%

Estrogen Deficiency-Associated Bone Loss in the Maxilla: A Methodology to Quantify the Changes in the Maxillary Intra-radicular Alveolar Bone in an Ovariectomized Rat Osteoporosis Model

Steck

Doan

et al. 2015

Tissue Engineering Part C: Methods

View full text Add to dashboard Cite

The effects of estrogen deficiency on bone characteristics are site-dependent, with the most commonly studied sites being appendicular long bones (proximal femur and tibia) and axial bones (vertebra). The effect on the maxillary and mandibular bones is still inconsistent and requires further investigation. This study was designed to evaluate bone quality in the posterior maxilla of ovariectomized rats to validate this site as an appropriate model to study the effect of osteoporotic changes. Forty-eight 3-month-old female Sprague-Dawley rats were randomly divided into two groups: an ovariectomized (OVX) group (n=24) and Sham-operated (SHAM) group (n=24). Six rats were randomly sacrificed from both groups at time points 8, 12, 16, and 20 weeks. The samples from tibia and maxilla were collected for micro computed tomography (μCT) and histological analysis. For the maxilla, the volume of interest area focused on the furcation areas of the first and second molar. Trabecular bone volume fraction (BV/TV, %), trabecular thickness (Tb.Th.), trabecular number (Tb.N.), trabecular separation (Tb.Sp.), and connectivity density (Conn.Dens) were analyzed after Micro CT scanning. At 8 weeks the indices BV/TV, Tb.Sp., Tb.N., and Conn.Dens showed significant differences (p<0.05) between the OVX and SHAM groups in the tibia. Compared with the tibia, the maxilla developed osteoporosis at a later stage, with significant changes in maxillary bone density only occurring after 12 weeks. Compared with the SHAM group, both the first and second molars of the OVX group showed significantly decreased BV/TV values from 12 weeks, and these changes were sustained through 16 and 20 weeks. For Tb.Sp., there were significant increases in bone values for the OVX group compared with the SHAM group at 12, 16, and 20 weeks. Histological changes were highly consistent with Micro CT results. This study established a method to quantify the changes of intra-radicular alveolar bone in the posterior maxilla in an accepted rat osteoporosis model. The degree of the osteoporotic changes to trabecular bone architecture is site-dependent and at least 3 months are required for the osteoporotic effects to be apparent in the posterior maxilla following rat OVX.

show abstract

Tooth loss and osteoporosis: to assess the association between osteoporosis status and tooth number

Abstract: Clinicians should inform osteoporotic patients they may be at greater risk of tooth loss and instigate more intensive preventive regimens for these individuals.

Cited by 49 publications

References 62 publications

Assessment the Relationship between Osteoporosis with Tooth Loss and Dry Mouth in Women with Osteoporosis

Assessment the Relationship between Osteoporosis with Tooth Loss and Dry Mouth in Women with Osteoporosis

Identifying dental panoramic radiograph features for the screening of low bone mass in postmenopausal women

Estrogen Deficiency-Associated Bone Loss in the Maxilla: A Methodology to Quantify the Changes in the Maxillary Intra-radicular Alveolar Bone in an Ovariectomized Rat Osteoporosis Model

Contact Info

Product

Resources

About