“…This compound is also known to have antimicrobial (Alma et al, 2003;Lourens et al, 2004), antioxidant (Lourens et al, 2004, Singh et al, 2006, anticarcinogenic (Kubo et al, 1996) and skin-penetration-enhancing properties (Cornwell & Barry, 1994). Essential oils containing this compound as a major component showed marked anti-inflammatory activity against carrageenan-and prostaglandin E 1 -induced edema in rats as well as anti-arthritic activity (Martin et al, 1993;Baricevic et al, 2001;Agarwal & Rangari, 2003). Oral administration of β-caryophyllene to rats significantly inhibited gastric mucosal injuries induced by acidic ethanol (Tamble et al, 1996) and DSS-induced experimental colitis, being useful in the prevention and treatment of colitis (Cho et al, 2007).…”