2018
DOI: 10.1097/sap.0000000000001297
|View full text |Cite
|
Sign up to set email alerts
|

Topical Antimicrobials in Burn Care

Abstract: Burn wounds disrupt the body’s primary defense against invasion and colonization by microorganisms. Topical antimicrobials are one component in burn wound care. These agents suppress microbial growth to advantage skin cells and wound healing. Topical antimicrobials can be divided into two superclasses: antiseptics and antibiotics. Herein we review the four main classes of topical antiseptics (emulsifiers, acids, oxidizers, and heavy metals) as well as antiseptic-impregnated dressings in current clinical use an… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
34
0
3

Year Published

2019
2019
2023
2023

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 25 publications
(37 citation statements)
references
References 113 publications
(120 reference statements)
0
34
0
3
Order By: Relevance
“…Compared to the broad array of antibiotics that are delivered systemically, the list of topical antibiotics is much smaller, including: bacitracin, neomycin, polymyxin, mupirocin, and fusidic agents. Antiseptics commonly used for topical treatment of wound infections can be divided into four broad classes: emulsifiers (chlorhexidine, octenidine, polyhexamethylene biguanide, benzalkonium salts), oxidizers (hydrogen peroxide, dilute hyperchlorite preparations, iodine compounds), acids (acetic acid, honey, boric acid), and heavy metals (silver compounds, bismuth compounds, copper, and mercury) [32,38]. Not all of these agents are commonly used for treatment of skin wounds, as some are used primarily to reduce microbial burden on the skin surface prophylactically (chlorhexidine, octenidine, povidone iodine), while others are often used for irrigation and wound cleansing capacities (chlorhexidine).…”
Section: Current Clinical Care Practices To Combat Skin Infectionsmentioning
confidence: 99%
See 4 more Smart Citations
“…Compared to the broad array of antibiotics that are delivered systemically, the list of topical antibiotics is much smaller, including: bacitracin, neomycin, polymyxin, mupirocin, and fusidic agents. Antiseptics commonly used for topical treatment of wound infections can be divided into four broad classes: emulsifiers (chlorhexidine, octenidine, polyhexamethylene biguanide, benzalkonium salts), oxidizers (hydrogen peroxide, dilute hyperchlorite preparations, iodine compounds), acids (acetic acid, honey, boric acid), and heavy metals (silver compounds, bismuth compounds, copper, and mercury) [32,38]. Not all of these agents are commonly used for treatment of skin wounds, as some are used primarily to reduce microbial burden on the skin surface prophylactically (chlorhexidine, octenidine, povidone iodine), while others are often used for irrigation and wound cleansing capacities (chlorhexidine).…”
Section: Current Clinical Care Practices To Combat Skin Infectionsmentioning
confidence: 99%
“…Not all of these agents are commonly used for treatment of skin wounds, as some are used primarily to reduce microbial burden on the skin surface prophylactically (chlorhexidine, octenidine, povidone iodine), while others are often used for irrigation and wound cleansing capacities (chlorhexidine). Below, we specifically discuss topical uses of silver ions and iodophor (iodine) compounds, as both have extensive clinical data describing their use in wound care [38].…”
Section: Current Clinical Care Practices To Combat Skin Infectionsmentioning
confidence: 99%
See 3 more Smart Citations