Topical application of serine proteases from Wrightia tinctoria R. Br. (Apocyanaceae) latex augments healing of experimentally induced excision wound in mice

Systematic investigation of ethanolic extract from Leea macrophylla : Implications in wound healing

“…Formation, alignment and contraction of extracellular matrix molecules determine the intactness of tissue. Reestablishment is critically dependent on the efficiency of reorganization of extra cellular matrix molecules (Yariswamy et al, 2013). The rise in granulation tissue mass and protein amount signifies increased cellular proliferation resulting in increased synthesis of collagen which is the principal extracellular protein in the granulation tissue (Fikru et al, 2012).…”

Transplanted adipose-derived stem cells can be short-lived yet accelerate healing of acid-burn skin wounds: a multimodal imaging study

“…Wound reduction analysis was performed as reported previously 48, 49 . Briefly, starting at day 5 post injury, wound boundaries at different days were traced on glass slides and copied on millimeter-indexed graph paper.…”

A novel form of ficin from Ficus carica latex: Purification and characterization

“…The properties of latex in plant defense and in alleviating various diseases have been attributed to the presence of several hydrolytic enzymes from which proteases play a key role. Most of the proteases found in latex of different plants belong to cysteine and serine proteases families (Singh et al, 2008;El Moussaoui et al, 2001;Azarkan et al, 2004Azarkan et al, , 2011Torres et al, 2012;Ramos et al, 2013;Yariswamy et al, 2013). Why latex contains high amounts of such proteases still remain enigmatic.…”