Topical steroids in burn patients: A systematic review of the literature and a descriptive analysis of topical KENACOMB use at a major tertiary burn centre

Duff, Michelle F; Lisec, Carl

doi:10.1016/j.jpra.2022.05.004

Cited by 3 publications

(1 citation statement)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Out of 397 participants, 11 of them used topical corticosteroids as skin moisturizers, 19 used them as chemical peels, 39 used them for whitening purposes, and five used them to treat rosacea. 'Burns' was selected as an indication by 11 responders despite the paucity of conclusive evidence on the outcomes of topical corticosteroids in treating inflammation and hypergranulation of burns in the literature [ 8 ]. Included in the inappropriate indications selected were 'Skin Infections' and 'Fungal Infections'.…”

Section: Discussionmentioning

confidence: 99%

Knowledge and Attitudes Towards Topical Corticosteroids Among Previous Users in the General Population of Saudi Arabia

Alamri,

Al Satti

2024

Cureus

View full text Add to dashboard Cite

Introduction Topical corticosteroids are a valuable tool for treating many dermatoses, offering anti-inflammatory and immunosuppressive properties. However, preexisting knowledge gaps and safety concerns may hinder treatment compliance. This study aims to evaluate knowledge and attitudes towards topical corticosteroids among former users within the general population of Saudi Arabia. Methods This cross-sectional study utilized an online survey to collect data. Knowledge was assessed through three dimensions: indications, proper use, and adverse reactions. Attitudes were assessed using the Topical Corticosteroid Phobia (TOPICOP) scale. Results Among the 397 respondents, 80.9% were females, 51.1% had suffered from a dermatological disease, and 76.3% had a bachelor's or higher educational level. When assessing knowledge, female participants (6.22±2.02) displayed significantly higher scores compared to male participants (5.26 ± 2.23) (p<0.001). Participants with dermatological diseases provided more accurate answers compared to those without. In assessing phobia towards topical corticosteroids, participants aged 18-25 years had lower topical corticosteroid phobia scores (31.06 ± 5.91), whereas those aged 56 years or more had higher scores (35.38 ± 6.04), p<0.001. Single participants had significantly lower topical corticosteroid phobia scores (32.27 ± 6.06) compared to those who were married (33.87 ±5.95) (p=0.010). Additionally, participants with dermatological diseases had higher scores in the behaviors subcategory despite having lower Global TOPICOP scores (32.58 ± 5.7) (p=0.033). Conclusion Enhancing knowledge about topical corticosteroids is crucial for mitigating corticophobia and promoting better adherence. To address gaps in knowledge, dermatologists should expand educational initiatives to include vulnerable populations, explicitly targeting males and older individuals.

show abstract

Section: Discussionmentioning

confidence: 99%

Knowledge and Attitudes Towards Topical Corticosteroids Among Previous Users in the General Population of Saudi Arabia

Alamri,

Al Satti

2024

Cureus

View full text Add to dashboard Cite

show abstract

Corticosteroid-loaded chitosan-based in-situ forming gel combined with microneedle technology for improvement of burn eschar wound healing

Barati,

Azadi,

Khoramjouy

et al. 2024

International Journal of Pharmaceutics

View full text Add to dashboard Cite

Recent advances in bioactive wound dressings

Nur,

Rahman,

Dip

et al. 2024

Wound Repair Regeneration

View full text Add to dashboard Cite

Traditional wound dressings, despite their widespread use, face limitations, such as poor infection control and insufficient healing promotion. To address these challenges, bioactive materials have emerged as a promising solution in wound care. This comprehensive review explores the latest developments in wound healing technologies, starting with an overview of the importance of effective wound management, emphasising the need for advanced bioactive wound dressings. The review further explores various bioactive materials, defining their characteristics. It covers a wide range of natural and synthetic biopolymers used to develop bioactive wound dressings. Next, the paper discusses the incorporation of bioactive agents into wound dressings, including antimicrobial and anti‐inflammatory agents, alongside regenerative components like growth factors, platelet‐rich plasma, platelet‐rich fibrin and stem cells. The review also covers fabrication techniques for bioactive wound dressings, highlighting techniques like electrospinning, which facilitated the production of nanofibre‐based dressings with controlled porosity, the sol–gel method for developing bioactive glass‐based dressings, and 3D bioprinting for customised, patient‐specific dressings. The review concludes by addressing the challenges and future perspectives in bioactive wound dressing development. It includes regulatory considerations, clinical efficacy, patient care protocol integration and wound healing progress monitoring. Furthermore, the review considers emerging trends such as smart materials, sensors and personalised medicine approaches, offering insights into the future direction of bioactive wound dressing research.

show abstract

Topical steroids in burn patients: A systematic review of the literature and a descriptive analysis of topical KENACOMB use at a major tertiary burn centre

Cited by 3 publications

References 24 publications

Knowledge and Attitudes Towards Topical Corticosteroids Among Previous Users in the General Population of Saudi Arabia

Knowledge and Attitudes Towards Topical Corticosteroids Among Previous Users in the General Population of Saudi Arabia

Corticosteroid-loaded chitosan-based in-situ forming gel combined with microneedle technology for improvement of burn eschar wound healing

Recent advances in bioactive wound dressings

Contact Info

Product

Resources

About