Handbook of Atopic Eczema
DOI: 10.1007/3-540-29856-8_52
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Topical Treatment with Glucocorticoids

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Cited by 6 publications
(10 citation statements)
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“…Indeed, comparative data demonstrating superior benefits [vs. topical corticosteroids (TC)] in rapid itch relief is lacking. 54 Although a staple of AD management, the regular use of TC in children has presented a practical challenge due to perceived systemic toxicity issues (i.e. hypothalamic -pituitary -adrenal axis suppression) traditionally associated with highly potent formulations.…”
Section: The Pharmacological Challenge Of Treating Pruritus In Childhmentioning
confidence: 99%
See 1 more Smart Citation
“…Indeed, comparative data demonstrating superior benefits [vs. topical corticosteroids (TC)] in rapid itch relief is lacking. 54 Although a staple of AD management, the regular use of TC in children has presented a practical challenge due to perceived systemic toxicity issues (i.e. hypothalamic -pituitary -adrenal axis suppression) traditionally associated with highly potent formulations.…”
Section: The Pharmacological Challenge Of Treating Pruritus In Childhmentioning
confidence: 99%
“…Finally, a relatively slower mechanism of action for TCIs would suggest later onset of symptom alleviation. Indeed, comparative data demonstrating superior benefits [vs. topical corticosteroids (TC)] in rapid itch relief is lacking 54 …”
Section: The Pharmacological Challenge Of Treating Pruritus In Childhmentioning
confidence: 99%
“…The basic principle of topical therapy with GCSs according to Ring [ 14 ] is their application in time “for as short as possible and as long as it is needed”. In the topical treatment of AD, the substances of high potency of action are only applied during exacerbation periods once a day for not more than 14 days.…”
Section: Discussionmentioning
confidence: 99%
“…In the performed study, the duration of prescribed treatment was shortened or even temporarily abandoned, in spite of the recommendations, by 64/141 (45.4%) patients. Interestingly enough, the symptoms of steroid phobia were observed only in 10% of patients with asthma and the greatest fear of GCSs therapy was found in patients who had never used that group of drugs [ 14 ].…”
Section: Discussionmentioning
confidence: 99%
“…Their clinical effectiveness in the treatment of psoriasis and atopic dermatitis is related to their vasoconstrictive, anti-inflammatory, immunosuppressive, and anti-proliferative effects (Kerscher et al, 1991;Wiedersberg et al, 2008). Mometasone furoate (MF) is a potent corticosteroid which presents an improved risk/benefit ratio.…”
Section: Introductionmentioning
confidence: 99%