TORCH INFECTIONS, PATHOGENICITY &amp; MORTALITY ASSESSMENTS

Morsy, Tosson A; HUSSEIN, HUSSEIN; MORSY, AYMAN

doi:10.21608/jesp.2022.235777

Cited by 3 publications

(2 citation statements)

References 78 publications

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“…It has many common names (Blue gum, Camphor oil) and belongs to the family Myrtaceae, in a study conducted on humans, it was revealed that human facial demodicosis when treated with freshly prepared camphor oil with or without glycerol dilutions gave complete cure with concentrations of 100%, 75% and 50% respectively [24]. Revealed that camphor oil with or without glycerol dilutions completely cured zoonotic scabies with concentrations of 100%, 75% and 50% within 5-10 days [25].…”

Section: Eucalyptus Globulusmentioning

confidence: 99%

Traditional medicinal plants and skin disease

2023

ICVPR

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Skin diseases are numerous and frequently occurring health problems affecting all ages from neonates to the elderly and cause harm in a number of ways. Maintaining healthy skin is important for a healthy body. Many people may develop skin diseases that affect the skin, including cancer, herpes and cellulitis. Some wild plants and their parts frequently used to treat these diseases. Using plants as old as a natural treatment is cheap and claimed to be safe. It is also suitable raw material for the production of new synthetic agents. A review of some plants for the treatment of skin diseases provided that summarizes the recent technological advancements that have taken place in the world during the past 20 years. The skin interfaces with the environment; it plays a key role in protecting the body against pathogens and excessive water loss. Its other functions are insulation, temperature regulation, sensation, storage and synthesis of vitamin D by action of ultraviolet (UV) and the protection of vitamin B folates, absorption of oxygen and drugs and water resistance Severely damaged skin will try to heal by forming scar tissue.

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Section: Eucalyptus Globulusmentioning

confidence: 99%

Traditional medicinal plants and skin disease

2023

ICVPR

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“…TORCH infections, which include toxoplasmosis, rubella, cytomegalovirus, and herpes virus, are known to cause significant prenatal, perinatal, and postnatal morbidity and mortality (Morsy et al, 2022). Infants may exhibit evidence of infection at birth, during infancy, or even years later.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Torch Infection Among Congenital Cataract Patients

BHUTTO,

ABRO,

KATPAR

et al. 2024

Biol Clin Sci Res J

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The objective of this descriptive cross-sectional study was to determine the frequency of TORCH infections among congenital cataract patients. The study was conducted at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, from September 22, 2021, to March 21, 2022. Patients meeting the inclusion criteria, including those diagnosed with congenital cataracts and TORCH infection within the age range of one day to ten years, were included after obtaining informed consent from their guardians. A slit lamp examination was performed to identify lens opacities indicative of congenital cataracts. Subsequently, patients with congenital cataracts were sent for laboratory investigation. TORCH infections were diagnosed based on IgM levels and clinical manifestations specific to each pathogen. The results revealed that the age range of the patients included in the study was one day to ten years, with a mean age of 17.9 ± 21.8 months. Of the 85 patients with congenital cataracts, 36 (42.5%) were male, and 49 (57.5%) were female. Interestingly, TORCH infection was identified in 17 (19.6%) patients with congenital cataracts, while the remaining patients showed no evidence of TORCH infection. In conclusion, TORCH pathogens, particularly cytomegalovirus and rubella virus, were found to be frequent causative agents of congenital cataracts. These findings highlight the importance of early diagnosis and management of TORCH infections in patients with congenital cataracts to prevent visual impairment and other associated complications.

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Persistent Inflammation Initiated by TORCH Infections and Dysbiotic Microbiome in Autism Spectrum Disorders: A Prospect for Future Interventions

Alibek¹,

Niyazmetova²,

Farmer³

et al. 2022

RIO

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Autism spectrum disorders (ASD) are a range of neurodevelopmental conditions that are clinically present early in childhood with the symptoms of social withdrawal and repetitive behavior. Despite an extensive research on ASD, no commonly accepted theory on the disease etiology exists. Hence, we reviewed several scientific publications, including reviews, preclinical and clinical investigations, and published hypotheses to analyze various opinions on the nature and cause of the disorder. Many studies suggest that infections and inflammation during pregnancy play a significant role in genetic and epigenetic changes in the developing fetus, resulting in an autistic phenotype in a child. Still, there is a lack of comprehensive literature about the multitude of autism inducing factors. Therefore, this article reviews and discusses available scientific evidence on the roles of viral, bacterial, fungal, and parasitic infections, overactivation of the immune system, and intestinal microflora in the pathogenesis and clinical manifestation of ASD. The overview of the scientific publications, including our own studies, suggests that TORCH infections, imbalanced microbiome, and persistent inflammation are significantly associated with the disruption of the social domain in ASD children. The ASD-related changes begin prenatally as maternal-to-fetal immune activation triggered by infection. It results in continuous low-grade inflammation and oxidative stress in a fetus, causing germline and somatic genetic changes in the developing brain and the establishment of the dysregulated immune system. These changes and dysregulations result in central and peripheral nervous systems dysfunctions as well as other comorbid conditions found in autistic children.

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TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS

Cited by 3 publications

References 78 publications

Traditional medicinal plants and skin disease

Traditional medicinal plants and skin disease

Frequency of Torch Infection Among Congenital Cataract Patients

Persistent Inflammation Initiated by TORCH Infections and Dysbiotic Microbiome in Autism Spectrum Disorders: A Prospect for Future Interventions

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