1996
DOI: 10.1093/oxfordjournals.ndt.a027475
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Torsade de pointes during low-dosage sotalol therapy in haemodialysis patients

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Cited by 12 publications
(6 citation statements)
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“…In our study, the only 2 variables which had a significant effect on the QTc interval were hypomagnesemia and hypokalemia. The QTc interval lengthening might have the potential of making our patients more vulnerable to TDP as reported by Huynh-Do et al (20). However, we did not observe any TDP attack in HD patients; this may LVFS: left ventricular fractional shortening, LVEF: left ventricular ejection fraction, LVPW: left ventricular posterior wall, A: peak velocity of late mitral flow, E: peak velocity of early mitral flow.…”
Section: Discussionsupporting
confidence: 46%
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“…In our study, the only 2 variables which had a significant effect on the QTc interval were hypomagnesemia and hypokalemia. The QTc interval lengthening might have the potential of making our patients more vulnerable to TDP as reported by Huynh-Do et al (20). However, we did not observe any TDP attack in HD patients; this may LVFS: left ventricular fractional shortening, LVEF: left ventricular ejection fraction, LVPW: left ventricular posterior wall, A: peak velocity of late mitral flow, E: peak velocity of early mitral flow.…”
Section: Discussionsupporting
confidence: 46%
“…The QTc interval lengthening might have the potential of making our patients more vulnerable to TDP as reported by Huynh‐Do et al. ( 20). However, we did not observe any TDP attack in HD patients; this may be due to the fact that none of our patients were using any medication including antiarrhythmia drugs.…”
Section: Discussionmentioning
confidence: 63%
“…Previous reports with the drug in patients on renal dialysis are of interest (17,18). To avoid the development of TdP, there have been attempts to correlate the degree of QT or QTc prolongation and QT dispersion (QTd), which might be of value in predicting the risk of TdP in the context of severe renal failure.…”
Section: Discussionmentioning
confidence: 99%
“…Only a few cases of TdP in patients on dialysis have been reported. Of the seven cases reported, two patients were on peritoneal dialysis, one developed acute renal failure during sotalol treatment, and four were on hemodialysis (17,18). All of the patients were on sotalol for supraventricular arrhythmia or AF.…”
Section: Discussionmentioning
confidence: 99%
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