Torsade de Pointes with severe vitamin D deficiency, an unusual presentation of a common problem

Halawa, Ahmad; Dave, Isha; Gautam, Sandeep

doi:10.1016/j.jccase.2019.07.003

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…In a case of a patient with severe vitamin D deficiency, hypocalcemia and prolonged QTc resulted in TdP and cardiac arrest. After the administration of vitamin D and calcium supplements, the QTc interval became normal, and the patient did not experience additional arrhythmic events [ 88 ]. A hypocalcemic teenage girl affected by hypoparathyroidism experienced a few episodes of syncope during exercise, and the ECG on admission showed prolonged QTc.…”

Section: Vitamin Dmentioning

confidence: 99%

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

et al. 2021

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A healthy regime is fundamental for the prevention of cardiovascular diseases (CVD). In inherited channelopathies, such as Brugada syndrome (BrS) and Long QT syndrome (LQTS), unfortunately, sudden cardiac death could be the first sign for patients affected by these syndromes. Several known factors are used to stratify the risk of developing cardiac arrhythmias, although none are determinative. The risk factors can be affected by adjusting lifestyle habits, such as a particular diet, impacting the risk of arrhythmogenic events and mortality. To date, the importance of understanding the relationship between diet and inherited channelopathies has been underrated. Therefore, we describe herein the effects of dietary factors on the development of arrhythmia in patients affected by BrS and LQTS. Modifying the diet might not be enough to fully prevent arrhythmias, but it can help lower the risk.

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Section: Vitamin Dmentioning

confidence: 99%

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

et al. 2021

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Malignant prolongation of the QTc interval due to severe vitamin D deficiency: an unusual presentation

et al. 2020

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Long QT syndrome with Torsades de Pointes (TdP) is a life-threatening polymorphic ventricular arrhythmia. The corrected QT (QTc) prolongation >500 milliseconds (ms) has been associated with TdP. Hypocalcaemia due to severe vitamin D deficiency is an uncommon cause of acquired long QT. We hereby present a case of a 40-year-old woman with sensorineural deafness and having symptoms of palpitations and presyncope. She had a QTc interval of 556 ms (reference range, QTc 451–470 ms in adult healthy woman) on 24-hour Holter analysis. Genetic analysis for congenital long QT syndrome was negative. She was diagnosed with severe hypocalcaemia secondary to severe vitamin D deficiency. After treatment with intravenous calcium gluconate, followed by oral vitamin D and calcium supplementation, the QTc became normalised and no further episode of palpitations or presyncope occurred. The causes of vitamin D deficiency was due to inadequate exposure to sunlight and a strict vegan diet.

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Torsade de Pointes with severe vitamin D deficiency, an unusual presentation of a common problem

Cited by 2 publications

References 7 publications

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

Malignant prolongation of the QTc interval due to severe vitamin D deficiency: an unusual presentation

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