Torulopsis Glabrata Urinary Infections: A Review

Frye, Karen; Donovań, John M.; Drach, George W.

doi:10.1016/s0022-5347(17)42880-1

Cited by 38 publications

(19 citation statements)

References 36 publications

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“…However, because isolation of bacteria in the urine samples was not controlled for, the authors acknowledged that bacteria may have been a possible cause of the pyuria reported. In another small study of Torulopsisglabrata urinary tract infections (UTIs), pyuria was present in eight of nine patients with invasive, symptomatic disease and in only 25 of 55 (45 %) believed to have asymptomatic colonization (5). However, eight of the nine patients with invasive disease had previous bacterial UTIs.…”

Section: Discussionmentioning

confidence: 99%

Frequency, pathogenicity and microbiologic outcome of non-Candida albicans candiduria

Occhipinti

Gubbins²,

Schreckenberger

et al. 1994

Eur. J. Clin. Microbiol. Infect. Dis.

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A retrospective review of urine cultures obtained from patients at the University of Illinois Hospital revealed that the frequency of isolation of non-albicans Candida species increased significantly from 1990 to 1991 (p = 0.0003), while the frequency of isolation of Candida albicans species decreased significantly (p = 0.0006). Patients with urine cultures positive for non-albicans Candida species of Torulopsis glabrata during 1991 were identified for review. Sixty-seven patients were eligible for evaluation. Non-albicans candiduria developed in an average of 12 days. Identical fungal species were isolated from the blood following a positive urine culture in only two patients. Twenty patients were treated; candiduria persisted in 9 (45%), while resolution occurred in 11 (55%). The remaining 47 patients were not treated. Non-albicans candiduria persisted in 30 (64%) of these patients and resolved in 15 (32%); in the remaining two patients (4%) the microbiologic outcome was undetermined. The difference in microbiologic outcomes between treated and untreated patients was not significant using the Chi-square test (p = 0.170). Non-albicans candiduria developed rapidly, frequently persisted whether treated or untreated, and rarely progressed to candidemia.

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Section: Discussionmentioning

confidence: 99%

Frequency, pathogenicity and microbiologic outcome of non-Candida albicans candiduria

Occhipinti

Gubbins²,

Schreckenberger

et al. 1994

Eur. J. Clin. Microbiol. Infect. Dis.

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“…Storfer et al [4] reported a slightly higher proportion of isolates due to C. glabrata. Risk factors for C. glabrata UTI are similar to those predisposing to C. albicans infection [15,16]. Non-albicans Candida species are also extremely common and far more prevalent than in other sites of Candida infection (oropharynx and vagina), possibly as a function of urine composition and pH selectivity for nonalbicans species.…”

Section: Microbiologymentioning

confidence: 99%

Management of candiduria

Sobel

Lundstrom

2001

Curr Urol Rep

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The distinction between Candida colonization of the urinary tract and infection is often blurred. Asymptomatic candiduria is particularly common in catheterized intensive care unit patients. To date, few studies have addressed the appropriate treatment regimens for candiduria. Fluconazole has become a mainstay of therapy; however, when to treat, whom to treat, and how long to treat are still largely unanswered questions. Asymptomatic nosocomial candiduria infrequently requires treatment intervention because morbidity is low and ascending infection and candidemia are rare complications. An understanding of the anatomic site of infection drives treatment decisions. More research is needed to define diagnostic criteria and therapeutic pathways. This review attempts to summarize the diagnosis and management of candiduria.

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“…Torulopsis glabrata (also known as C. glabrata) exist as saprophytes in the oral cavity, alimentary canal, respiratory tree, and asymptomatic urinary colonization [11]. Diabetes mellitus, antibiotic therapy, surgery, and obstructive uropathy have been associated with T. glabrata infections of the kidneys and bladder [11,12].…”

Section: Infections Caused By Candida Speciesmentioning

confidence: 99%