Total and differential leukocyte counts percentiles in normal pregnancy

Lurie, Samuel; Rahamim, Einam; Piper, Irena; Golan, Abraham; Sadan, Oscar

doi:10.1016/j.ejogrb.2006.12.013

Cited by 102 publications

(88 citation statements)

References 8 publications

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“…Similarly, a study by Lurie et al among pregnant women reported that the leukocyte and neutrophil counts gradually and significantly increased form the 1 st to the 3 rd trimester [8].…”

Section: Discussionmentioning

confidence: 99%

Haematological Indices of Nigerian Pregnant Women

Oa¹,

Oa²,

Mm³

2017

J Blood Lymph

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Haematological profile to a large extent, reflects the overall well-being or otherwise of an individual. Anaemia, thrombocytopaenia and leucocytosis are among the most common changes observed in the haematological parameters of pregnant women. Paucity of documented reference values for pregnant women from this region necessitated this study, considering the importance of these parameters, the potential implication of its wrong interpretation and application and their effects on pregnancy and its outcome. A total of 253 women, aged 15-50 years were recruited. Two hundred and eleven of them were pregnant and 42 were non pregnant control. Assessment of some key haematological parameters showed higher WBC and ANC and lower platelets, Hb and ALC in the pregnant compared to the non-pregnant women (p<0.05). It also showed higher WBC and ANC and lower platelets and haemoglobin concentration with increasing trimester (p<0.05).

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“…Similarly, a study by Lurie et al among pregnant women reported that the leukocyte and neutrophil counts gradually and significantly increased form the 1 st to the 3 rd trimester [8].…”

Section: Discussionmentioning

confidence: 99%

Haematological Indices of Nigerian Pregnant Women

Oa¹,

Oa²,

Mm³

2017

J Blood Lymph

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“…Endogenous oestrogens modulate the effector cells of specific and non-specific immune systems: directly -by interacting with oestrogen receptors, or indirectly -by inducing the production of soluble mediators or the expression of their receptors (Chighizola and Meroni 2012). Supraphysiological levels of 17β-estradiol (E2) during pregnancy or hormone replacement therapy cause neutrophilia and/or an increase in WBC counts (Bergstrrm et al 2006, Lurie et al 2008. Neutrophil counts generally increase in acute infectious and non-infectious inflammations, during intoxication and in certain metabolic diseases.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of selected serum biochemical and haematological parameters in gilts exposed per os to 100 ppb of zearalenone

Jakimiuk¹,

Radwińska²,

Pomianowski³

et al. 2015

Polish Journal of Veterinary Sciences

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Zearalenone (ZEN) widely contaminates animal feed of plant origin. The recommended safe concentrations of ZEN in feeds for various animal species are set mainly based on the mycotoxin's hormonal properties (NOEL). Our growing knowledge about biologically active concentrations of ZEN, molecular mechanisms and cells/tissues targeted by ZEN indicates that the harmful effects exerted by this mycotoxin on animals may be far greater than previously believed. This experiment was performed on pre-pubertal gilts divided into a control group (n=9) and an experimental group (ZEN, n=9). The control group received placebo, whereas the experimental group was administered ZEN at a dose of 0.1 mg/kg feed (equivalent to 5 μg/kg BW/day) for 42 days. On days 14, 28 and 42 blood samples were collected from the animals to determine the concentrations of selected zearalenols, serum biochemical and haematological parameters. Conjugated ZEN was found in the blood serum of the experimental gilts. Changes in the analysed biochemical parameters included a transient increase in albumin and cholesterol levels. A statistically significant increase in the concentrations of neutrophilic and acidophilic granulocytes was observed in the white blood cell system. The results indicate that long-term per os exposure of pre-pubertal gilts to low doses of ZEN (below NOEL) has a modulatory effect on liver function and white blood cells.

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“…19 Our data showed increased neutrophils count (percentages and absolute values) in 5 cases (83.3%), decreased eosinophils and lymphocytes percentages in all cases (100%) in the first trimester maternal peripheral blood testing in comparison to normal gestational aged matched pregnancy. Given our limited number of cases, however it may suggest an exaggerated maternal immune-inflammatory response associated with CHI cases.…”

mentioning

confidence: 92%