Total body and exchangeable potassium in chronic airways obstruction: a controversial area?

Boddy, K.; Davies, David; Howie, A. D.; Madkour, Mk; Mahaffy, M E

doi:10.1136/thx.33.1.62

Cited by 6 publications

(3 citation statements)

References 13 publications

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“…However, the present study shows no correlation between completeness of equilibration at 24 or 48 hours and indices of renal function. It is perhaps interesting to note that the patients with chronic bronchitis studied by Boddy et al (1978) had all experienced one or more episodes of fluid retention, but at the time of study they were, as were our patients, free from oedema.…”

Section: Discussionmentioning

confidence: 57%

“…By using the longer half-life isotope 43K and taking samples up to 64 hours after giving the tracer, they found that equilibration was significantly delayed. The same group of workers (Boddy et al, 1978) also found delayed equilibration in patients with chronic bronchitis. Therefore, the effect of basing an estimate of exchangeable potassium on samples taken at around 24 hours may well underestimate the true value of body potassium.…”

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confidence: 72%

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Whole body potassium and total exchangeable potassium in elderly patients with cardiac-failure.

Lye¹,

Winston²

1979

Heart

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Body potassium status of patients with cardiac failure may be estimated by a number of methods, but increasing reliance is being placed upon radioisotope dilution with 42K which measures the total exchangeable potassium. Total exchangeable potassium comprises between 86 per cent and 97 per cent of whole body potassium in healthy subjects. We have measured total exchangeable potassium in 22 oedema-free elderly patients with stable cardiac failure and compared the results with simultaneously determined measurements of whole body potassium obtained by whole body counting. The mean whole body potassium was 2360 +/- 640 mmol. The mean value of total exchangeable potassium measured at 24 hours was 1820 +/- 610 mmol (77% of whole body potassium) and increased further to 2000 +/- 600 mmol (84%) when measured after 48 hours. In patients with cardiac failure and, perhaps, also other patients with a history of fluid retention, the mixing of a tracer dose may be significantly delayed, which if not appreciated may lead to an overestimate of potassium depletion.

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Section: Discussionmentioning

confidence: 57%

mentioning

confidence: 72%

Whole body potassium and total exchangeable potassium in elderly patients with cardiac-failure.

Lye¹,

Winston²

1979

Heart

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show abstract

“…This discrepancy was considered to be due either to exchangeable potassium being a smaller fraction of body potassium in patients with COAD than in normal subjects or due in part to insufficient equilibration time used in isotope dilution studies (Boddy et al, 1978).…”

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confidence: 99%