Total intravenous anaesthesia in a developing environment

Mato, CN; Eguma, SA; Eshiet, A I; Akpan, S

doi:10.4314/phmedj.v1i2.38859

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It also reduces theatre pollution. (2) The advantages of TIVA using propofol include rapid and smooth induction without significant haemodynamic alterations, good maintenance of anaesthesia, less incidence of postoperative nausea and vomiting (PONV), faster and better recovery profile resulting in higher patient satisfaction. (3) As a consequence of these favourable indices, Propofol remains widely used for gynecological, neurosurgical, and day-case anaesthesia.…”

Section: Introductionmentioning

confidence: 99%

Total Intravenous Anaesthesia with Propofol-a comparison of Target-controlled infusion (TCI) with manual controlled infusion (MCI). A randomized study

Jasper

Efe

Nosa

et al. 2022

Preprint

View full text Add to dashboard Cite

Background Total Intravenous Anaesthesia (TIVA) with propofol infusion is done by manual co’ntrolled infusion (MCI) or by target-controlled infusion (TCI) devices. This is a comparative study of MCI/TCI administration. Method In this randomized controlled trial, Anaesthesia was induced with propofol 1%, using a target blood concentration of 5 Meg/ml in the TCI group or at a dose of 1.5 mg/kg at an infusion rate of 1200 ml/h in the MCI group. Subsequently, a step-down maintenance regimen (10, 8 and 6 mg/kg/h at 10-min interval) was commenced for the MCI group. Primary outcome was the time to induction of anaesthesia in both groups. Data was analysed using Statistical Package for Social Sciences (SPSS) version 20.0. Results 52 patients were recruited into the study. The duration of induction of anaesthesia in the TCI group compared to the MCI group was (94.62 ± 11.34 sec vs. 79.50 ±16.23 sec, p = 0.001). The induction dose of propofol TCI against MCI was (118.00 ± 22.33 mg vs.133.04 ± 20.58 mg, p = 0.015). Both groups were comparable in terms of total dose of propofol (I 152.92 ± 234.47 mg vs. 1014.97 ± 264.18 mg, p = 0.052), recovery time (8.45 ± 2.13 min vs. 7.86 ± 2.05 min, p = 0.314), haemodynamic parameters and incidence of adverse events. Conclusion Manual controlled infusion was comparable to target controlled infusion for the induction and maintenance of general anaesthesia using propofol; providing similar quality and ease of anaesthesia as a viable option in resource challenged settings.

show abstract

Section: Introductionmentioning

confidence: 99%