Total Motile Sperm Count Trend Over Time: Evaluation of Semen Analyses From 119,972 Men From Subfertile Couples

Tiegs, Ashley W.; Landis, Jessica; Garrido, Nicolás; Scott, Richard T.; Hotaling, James

doi:10.1016/j.urology.2019.06.038

Cited by 48 publications

(26 citation statements)

References 29 publications

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“…Fifteen peer-reviewed research studies comprised the primary citations used by 34 of the 52 total articles links ( Table 4 ) [ 9 10 11 12 13 14 15 16 17 18 19 20 21 22 ]. The remaining 18 links did not cite original peer-reviewed scientific studies, or purported study data were not accessible.…”

Section: Resultsmentioning

confidence: 99%

Social Media Sensationalism in the Male Infertility Space: A Mixed Methodology Analysis

Zaila

Osadchiy

Shahinyan

et al. 2020

World J Mens Health

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Section: Resultsmentioning

confidence: 99%

Social Media Sensationalism in the Male Infertility Space: A Mixed Methodology Analysis

Zaila

Osadchiy

Shahinyan

et al. 2020

World J Mens Health

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“…Total motile sperm count (TMSC) is most frequently examined and cited in relation to IUI success, 3,4 but a recent systematic review and meta‐analysis clearly presents the lack of robust evidence for clear lower cut‐off levels of TMSC in IUI treatment 5 . Hence, one cannot define threshold levels of TMSC at which IUI should be withheld.…”

Section: Introductionmentioning

confidence: 99%

“…1 Normal semen quality is usually verified using WHO criteria, but these values are not defined to be clinically applicable for fertility treatment, and pregnancy rates after IUI are acceptable even when counts are below the WHO thresholds for normal semen quality. 2 Total motile sperm count (TMSC) is most frequently examined and cited in relation to IUI success, 3,4 but a recent systematic review and meta-analysis clearly presents the lack of robust evidence for clear lower cut-off levels of TMSC in IUI treatment. 5 Hence, one cannot define threshold levels of TMSC at which IUI should be withheld.…”

Section: Introductionmentioning

confidence: 99%

Prewash and postwash total progressively motile sperm counts have poor predictive value for clinical pregnancy after intrauterine insemination

Liu

Chen

Wang

et al. 2020

Intl J Gynecology & Obste

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Objective To evaluate the predictive value of the prewash and postwash total progressively motile sperm counts (TPMSC) on clinical pregnancy after intrauterine insemination (IUI) . Methods A review of medical records of women undergoing 2064 IUI cycles in a university hospital between April 2010 and October 2018. Results No pregnancies were seen when the prewash TPMSC was less than 9 million or the postwash TPMSC was less than 2 million. There was no correlation between TPMSC and clinical pregnancies. Further analysis was made in pregnancies after prewash TPMSC of 3–10 million and more than 10 million, and after postwash TPMSC of 10–100 million and more than 100 million. No correlation was found between TPMSC and clinical pregnancy in different strata of female age, infertility duration, type of infertility, type of IUI treatment, and the number of treatment cycles. A negative relationship was found for unstimulated IUI treatment and the number of treatment cycles. The prewash and postwash TPMSC showed no predictive value. Conclusion Prewash and postwash TPMSC have poor predictive value for clinical pregnancy in IUI. Cycles with a prewash TPMSC of 10–100 million or postwash TPMSC of 3–10 million could achieve acceptable pregnancy rates with IUI.

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“…The fact of global decline in male fertility is undeniable and was inferred from studies on sperm count in men across the world. The decline in this index was estimated from 10% [1] up to tremendous 60% in some regions [2]. The list of potential causes of lower or lack of fertility is long and variable and among others it consists of various infections, genetic diseases, or environmental factors, the infertility can be the symptom of hypogonadism as well.…”

Section: Introduction and Purposementioning

confidence: 99%

Male hypogonadism with its systemic complications

Niedobylski

Laszczak

Warchoł

et al. 2020

J Educ Health Sport

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Introduction and purpose: Total lack of testosterone or its level lower than 9-12 mmol/L (250-350 ng/dL) of serum in men is called hypogonadism. Due to the importance of testosterone in male body, hypogonadism usually causes a variety of symptoms, mostly of sexual naturelack of libido, erectile dysfunction, infertility and associated psychological problems, it can though be the cause of more dangerous changes in the male body. The purpose of this study is to review possible systemic complications of male hypogonadism (with the emphasis on hypogonadotropic hypogonadism) apart from those sex-related. State of knowledge: The lack of testosterone and gonadotropins was proven to cause a number of negative changes in different systems and various clinical situations. It can negatively impact the condition of skeletal system. Although testosterone is widely thought to increase cardiovascular risk some studies show that the hypogonadism has a negative impact on it as well. Some studies hypothesised the role of hypogonadism in anaemia development, but generally it isn't taken into account in investigation of this condition. Some studies show the impact of hypogonadism on higher risk of some metabolic and endocrine diseases. The most interesting conclusions were found in literature on oncological implications of testosterone and lack of it. It turns out that there is a number of studies showing the positive impact of relatively higher testosterone concentrations while androgen deprivation therapy is the main therapeutic option in advanced prostate cancer. Conclusions: Due to very unpleasant and possibly dangerous complications of hypogonadism endocrinologists should stay alert to signs of hypogonadism to be able to start testosterone replacement in the right moment.

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Total Motile Sperm Count Trend Over Time: Evaluation of Semen Analyses From 119,972 Men From Subfertile Couples

Cited by 48 publications

References 29 publications

Social Media Sensationalism in the Male Infertility Space: A Mixed Methodology Analysis

Social Media Sensationalism in the Male Infertility Space: A Mixed Methodology Analysis

Prewash and postwash total progressively motile sperm counts have poor predictive value for clinical pregnancy after intrauterine insemination

Male hypogonadism with its systemic complications

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