Total nasal resistance among Sasang constitutional types: a population-based study in Korea

Abstract

BackgroundThere have been many attempts to find an objective phenotype by Sasang constitutional types (SCTs) on an anatomical, physiological, and psychological basis, but there has been no research on total nasal resistance (TNR) among SCTs.MethodsWe assessed the value of the TNR in the SCTs classified by an integrated diagnostic model. Included in the study were 1,346 individuals (701 males, 645 females) who participated in the Korean Genome and Epidemiology Study (KoGES). The TNR was measured by active anterior rhinomanometry (AAR) at transnasal pressures of 100 and 150 Pascal (Pa).ResultsThe average TNR was 0.186 ± 0.004 Pa/cm3/second at 100 Pa in the Tae-eum (TE), 0.193 ± 0.007 in the So-eum (SE), and 0.208 ± 0.005 in the So-yang (SY) types. Under condition of 150 Pa the TE type had a TNR value of 0.217 ± 0.004, the SE type was 0.230 ± 0.008, and the SY type was 0.243 ± 0.005. Higher values of TNR were more likely to be reported in the SY type at 100 Pa and 150 Pa. In the stratified analysis by sex, the SY type in males and females tended to have higher TNR value than the TE and SE types at transnasal pressure of both 100 Pa and 150 Pa.ConclusionsThese results provide new approaches to understand the functional characteristics among the SCTs in terms of nasal physiology. Further studies are required to clarify contributing factors for such a difference.

Cohort Profile: The Korean Genome and Epidemiology Study (KoGES) Consortium

“…height, weight, waist circumference, blood pressure, blood count, biochemical analysis, including blood sugar, lipid profiles and other biomarkers to evaluate current health status; Table 4 ). In addition to the core variables, the KoGES has also been promoting various ancillary and collaborative measurements and studies, including oral glucose tolerance test, carotid intima-media thickness test, pulse wave velocity (PWV) test, electrocardiography, pulmonary function test, bone mineral density, brain magnetic resonance imaging, osteoporosis, periodontal diseases and oriental medicine study, 7 , 8 that lead to numerous in-depth research outcomes. A list of these special clinical tests is shown in Supplementary Table 4 (available as Supplementary data at IJE online).…”

Recent progress and prospects in Sasang constitutional medicine: A traditional type of physiome-based treatment

“…Lee showed that the TE constitution is an independent risk factor for obstructive sleep apnea (Lee et al, 2013a). Yoon evaluated the total nasal resistance for the Sasang constitution in young males, as well as six syndromes in patients with functional dyspepsia compared with healthy subjects; the study found that SE constitution is primarily related to functional dyspepsia (Yoon et al, 2013). Ahn performed an association study to compare subclinical hypothyroidism and the Sasang constitutions (Ahn et al, 2012).…”