Total Oesophageal Obstruction in Association with Combined Enteral Feed and Sucralfate Therapy

Sj, Rowbottom; Wilson, John T.; Samuel, Leslie; Is, Grant

doi:10.1177/0310057x9302100327

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Cited by 12 publications

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“…[48] Interestingly, laboratory findings by Rowbottom et al . [9] showed that increasing acidity (pH < 4) causes increased viscosity and precipitation of sucralfate and enteral feeding formulas, independently or when mixed together.…”

Section: Discussionmentioning

confidence: 99%

Enteral feed obstructing its own way

Kesarwani¹,

Ghelani²,

Reece³

2010

Indian Journal of Critical Care Medicine

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Esophageal obstruction due to solidified enteral feeds is a rare but distressful complication in intensive care unit (ICU) patients. It has been suggested that gastroesophageal reflux, very low gastric pH, decreased pepsin and pancreatic enzyme secretions may be responsible for the solidification of casein containing enteral formulas. Recognition and avoidance of these factors will prevent such complication.

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Section: Discussionmentioning

confidence: 99%

Enteral feed obstructing its own way

Kesarwani¹,

Ghelani²,

Reece³

2010

Indian Journal of Critical Care Medicine

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Safety of Sucralfate

Mathews¹,

Dahl²

1995

Sucralfate

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Esophageal obstruction by solidification of the enteral feed: a complication to be prevented

García-Luna

García

Pereira

et al. 1997

Intensive Care Medicine

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We report three cases of esophageal obstruction due to solidification of enteral feed refluxed from the stomach in patients being fed through a nasogastric tube. All three patients were administered sucralfate continuously by tube. The few previous descriptions of this rare complication have also implicated sucralfate with its pathogenesis. Given its clinical importance and the growing use of long-term enteral nutrition, this adverse event needs to be considered.

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Total Oesophageal Obstruction in Association with Combined Enteral Feed and Sucralfate Therapy

Abstract: Physical or chemical interactions between enteral feeding solutions and drugs are uncommon but may lead to relatively serious complications. We report a case of total oesophageal obstruction in a patient receiving Sucralfate suspension and Ensure Plus enteral feed.

Cited by 12 publications

References 9 publications

Enteral feed obstructing its own way

Enteral feed obstructing its own way

Safety of Sucralfate

Esophageal obstruction by solidification of the enteral feed: a complication to be prevented

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