1993
DOI: 10.1016/s0022-3468(05)80311-2
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Total parenteral nutrition-associated cholestasis: Clinical and histopathologic correlation

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Cited by 97 publications
(53 citation statements)
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“…The severity of such as liver abscess or ascending cholangitis. Sepsisassociated cholestasis is more common with gram-negaillness appears to correlate with the duration of TPN therapy [15]. In addition, TPN-associated cholestasis is tive infections.…”
Section: Total Parenteral Nutrition Total Parenteral Nutrition (Tpn) mentioning
confidence: 99%
“…The severity of such as liver abscess or ascending cholangitis. Sepsisassociated cholestasis is more common with gram-negaillness appears to correlate with the duration of TPN therapy [15]. In addition, TPN-associated cholestasis is tive infections.…”
Section: Total Parenteral Nutrition Total Parenteral Nutrition (Tpn) mentioning
confidence: 99%
“…More specific, the hepatic uptake of fatty acids and triglycerides and their rates of synthesis, the secretion of these compounds via plasma or bile, or the hydrolysis of triglycerides or oxidation of fatty acids may be altered (21). These mechanisms may also be important in the development of hepatic steatosis as a result of the prolonged use of total parenteral nutrition, as some investigators have proposed that deficiencies or toxicities of the parenteral nutrition solution may lead to hepatic injury (22)(23)(24).…”
mentioning
confidence: 99%
“…Finally, it is important to note that although the PELD includes the patient's bilirubin level as an indicator of liver injury and cholestasis, an elevated bilirubin level does not seem to correlate well with histologic evidence of liver injury (37)(38)(39).…”
Section: Discussionmentioning
confidence: 99%