Total Parenteral Nutrition in the Critically Ill Patient: a Meta-analysis

Heyland, Daren K.; MacDonald, Shaun; Keefe, Laurie; Drover, John W.

doi:10.1097/00132586-199908000-00015

Cited by 223 publications

(338 citation statements)

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“…However, it is suggested that infection frequency does not increase for patients treated with TPN and that non-infection complications are rarely observed (15). No statistically significant difference was determined in our study between the groups with regard to infectious complications.…”

Section: Discussioncontrasting

confidence: 66%

Effects of enteral and total parenteral nutrition on length of stay in intensive care unit in postoperative period

Aydoğan¹,

Paşahan²,

Karademir³

et al. 2017

Med-Science

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Patients post-operatively followed in intensive care units in are known to have high morbidity and mortality rates. The aim of the present study was to compare the effects of enteral versus total parenteral nutrition for length of ICU stay in postoperative patients. Nutritional support for patients were divided into two groups; enteral nutrition (Group E) total parenteral administered (Group P). Demographic findings, APACHE II score and serum albumin levels were determined in the preoperative period in both groups of patients. In both groups were recorded type of operation and blood transfusion during the operation. Gas, fecal discharge time in the postoperative period, of patients in groups and, postoperative day 7th, serum albumin, and serum C-reactive protein (CRP), length of stay intensive care unit and mortality rates were determined. Abdominal cramps, the tension in the abdomen, nausea and diarrhea in patients in group E were accepted as complications of enteral nutrition. In this study were included group E 89, group P 82 patients. Between groups were similar demographic features, APACHE II score and serum albumin levels. Both groups was not significant difference operation type, operation time and blood transfusion. Postoperative gas discharge and fecal discharge were significantly difference earlier period in Group E (p <0.05). In terms of the serum albumin and CRP levels were not significant difference between groups postoperative day 7th. Gastrointestinal complications was detected in Group E 58.5% and in Group P 28.9%. Both groups showed two patients mortality in postoperative period. The median length of ICU stay was shorter Group E versus Group P in postoperative period (p <0.05). In the postoperative period the implementation of enteral nutrition was associated with the decreased length of ICU stay and recovered earlier gastrointestinal function. We thought that enteral nutrition support can be used safely and priority postoperative patients in ICU.

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Section: Discussioncontrasting

confidence: 66%

Effects of enteral and total parenteral nutrition on length of stay in intensive care unit in postoperative period

Aydoğan¹,

Paşahan²,

Karademir³

et al. 2017

Med-Science

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“…increase the rate of infectious complications and cardiovascular morbidity. 104,105 In North America, provision of hypocaloric glucose at a dose below the patient's actual energy requirement is still being used to ''feed'' patients after elective abdominal surgery. Nevertheless, the anticatabolic properties of hypocaloric glucose observed in healthy fasting subjects do not apply to patients after surgical trauma.…”

Section: Nutritionmentioning

confidence: 99%

Perioperative catabolism

Schricker

Lattermann

2015

Can J Anesth/J Can Anesth

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“…Among severely malnourished patients, however, parenteral nutrition was associated with a decrease in noninfectious complications (87). A recent meta-analysis by Heyland and coworkers reviewed 26 randomized trials comparing total parenteral nutrition with standard care in a total of 2211 surgical and critically ill patients (88). The authors found no survival benefit of total parenteral nutrition and noted possible harm among patients in a medical ICU treated with total parenteral nutrition.…”

Section: Nutritional Supportmentioning

confidence: 99%