Total Pelvic Exenteration With Distal Sacrectomy for Fixed Recurrent Rectal Cancer in the Pelvis

Moriya, Yoshihiro; Aoki, Takayuki; Fujita, Shin; Yamamoto, Seiichirou

doi:10.1007/s10350-004-0714-9

Cited by 143 publications

(141 citation statements)

References 22 publications

(25 reference statements)

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“…Необходимо отметить, что онкологические результаты ЭМТ, выполненных по поводу реци-дивных опухолей прямой кишки, существенно уступают таковым при первичном РПК. Показатель 5-летней общей выживаемости после ЭМТ по поводу рецидивных опухолей в среднем не превы-шает 20-25% [10], тогда как ЭМТ по поводу первичного местно-распространенного РПК позволяет его увеличить до 30-55% [11].…”

Section: Abstract: Locally Advanced Rectal Cancer Small Pelvic Exenunclassified

Patient follow-up after total small pelvic exenteration for locally advanced rectal cancer

Сидоров¹,

Alekseev²,

Ложкин³

et al. 2015

Onkol. Z. im. P.A. Gercena

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Section: Abstract: Locally Advanced Rectal Cancer Small Pelvic Exenunclassified

Patient follow-up after total small pelvic exenteration for locally advanced rectal cancer

Сидоров¹,

Alekseev²,

Ложкин³

et al. 2015

Onkol. Z. im. P.A. Gercena

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“…Symptoms were classified according to presence of pain in 23 studies (Table 1), and 50% (796 of 1607) of patients were symptomatic with pain (S2). Five studies 4,14,31,33,39 reporting on symptoms had a clinically relevant patient selection (sacral resection or intraluminal recurrence only). After exclusion of these studies, the rates of S0 and S2 clinical presentation were 30% (563 of 1884) and 47% (700 of 1491), respectively.…”

Section: Clinical Presentation Of Local Recurrencementioning

confidence: 99%

“…A macroscopically complete resection (R0/R1) could be achieved in a median of 85% (range 31%-100%) of patients in 38 studies ( Table 2). Part of the sacrum was included in the resection in all patients in 5 studies 12,14,33,40,51 and in no patients in another 17 studies (Table 2). In the remaining 20 studies reporting on sacral resection, the median rate was 13% (range 2%-73%; Table 2).…”

Section: Surgery For Local Recurrencementioning

confidence: 99%

Intentionally curative treatment of locally recurrent rectal cancer: a systematic review

Tanis

Doeksen

Lanschot

2013

cjs

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Intentionally curative treatment of locally recurrent rectal cancer: a systematic reviewBackground: There is a lack of outcome data beyond local recurrence rates after primary treatment in rectal cancer, despite more information being necessary for clinical decision-making. We sought to determine patient selection, therapeutic modalities and outcomes of locally recurrent rectal cancer treated with curative intent. Methods:We searched MEDLINE (1990-2010) using the medical subject headings "rectal neoplasms" and "neoplasm recurrence, local." Selection of cohort studies was based on the primary intention of treatment and availability of at least 1 outcome variable. Results:We included 55 cohort studies comprising 3767 patients; 8 studies provided data on the rate of intentionally curative treatment from an unselected consecutive cohort of patients (481 of 1188 patients; 40%). Patients were symptomatic with pain in 50% (796 of 1607) of cases. Overall, 3088 of 3767 patients underwent resection. The R0 resection rate was 56% (1484 of 2637 patients). The rate of external beam radiotherapy was 100% in 9 studies, 0% in 5 studies, and ranged from 12% to 97% in 37 studies. Overall postoperative mortality was 2.2% (57 of 2515 patients). Five-year survival was at least 25%, with an upper limit of 41% in 11 of 18 studies including at least 50 resections. We found a significant increase in reported survival rates over time (r 2 = 0.214, p = 0.007). Conclusion:More uniformity in treatment protocols and reporting on outcomes for locally recurrent rectal cancer is warranted. The observed improvement of reported survival rates in time is probably related to better patient selection and optimized multimodality treatment in specialized centres.

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“…Específicamente el cáncer de recto constituye aproximadamente un tercio de los casos y su resección quirúrgica es la principal opción curativa para la enfermedad primaria [1][2] .…”

Section: Introductionunclassified

“…A pesar de los grandes avances actuales en el tratamiento multidisciplinario de estos pacientes la tasa de recaída local observada en el promedio de los centros generales y hospitales de la comunidad oscila desde 5.3% hasta el 20-22% constituyendo entonces un problema con una incidencia significativa en la práctica oncológica que habitualmente resulta de difícil resolución, por lo complejo de las resecciones quirúrgicas que implica [2][3][4][5] .…”

Section: Introductionunclassified

Resecciones multiviscerales en el Tratamiento Quirúrgico de las Recaídas Locoregionales de Cirugía de RectoSigma. Factibilidad, Complicaciones y Resultados Oncológicos

Mandojana

Zalazar

Pairola

et al. 2016

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Las inmunodeficiencias primarias (IDP) son enfermedades de baja prevalencia. Existen signos de alarma para su sospecha clínica. Los objetivos fueron describir características clínicas y signos de alarma de pacientes con IDP y comparar diferencias clínicas entre déficit selectivo de inmunoglobulina A (IgA) y otras IDP. Se estudiaron 89 pacientes, con mediana de edad, al momento del diagnóstico, de 6 años (4,08-11,67). 53 (59,5%) pacientes, varones. 54 (60,7%) pacientes, con déficit selectivo de IgA, y 35 (39,3%), con otras IDP. Las principales manifestaciones clínicas fueron rinofaringitis en 65 (73,03%) pacientes y atopia en 39 (43,82%) pacientes. Presentaron signos de alarma 24 (26,97%) pacientes, ninguno con déficit selectivo de IgA. En los pacientes con otras IDP, se observó mayor incidencia de infección respiratoria baja, sepsis, infecciones cutáneas, candidiasis mucocutánea, alteraciones dentales, malformaciones cardiovasculares, angioedema, internaciones y mortalidad. 10 (28,57%) pacientes recibieron gammaglobulina endovenosa; 15 (42,85%), antibiótico-profilaxis; y 2 (2,24%), antimicóticoprofilaxis. Palabras clave: infecciones respiratorias, hipersensibilidad, gammaglobulinas, síndromes de inmunodeficiencia, deficiencia de IgA.

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Total Pelvic Exenteration With Distal Sacrectomy for Fixed Recurrent Rectal Cancer in the Pelvis

Cited by 143 publications

References 22 publications

Patient follow-up after total small pelvic exenteration for locally advanced rectal cancer

Patient follow-up after total small pelvic exenteration for locally advanced rectal cancer

Intentionally curative treatment of locally recurrent rectal cancer: a systematic review

Resecciones multiviscerales en el Tratamiento Quirúrgico de las Recaídas Locoregionales de Cirugía de RectoSigma. Factibilidad, Complicaciones y Resultados Oncológicos

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