Total Phenol Content and Antioxidant Activity of Mosses From Yenice Forest (Ida Mountain)

Aslanbaba, Burcu; Yayıntaş, Özlem Tonguç; Özyurt, Dilek; Öztürk, Birsen Demirata

doi:10.26900/jsp.2017.0

Cited by 17 publications

(18 citation statements)

References 10 publications

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“…Some of the bryophytes secondary metabolites exhibit diverse biological activities such as cytotoxicity, antimicrobial, antifungal, antitumor, antioxidant, anti-inflammatory, and many others [ 1 , 6 ]. The biological activity of a certain plant extract depends on several factors such as chemical composition and structural configuration of functional groups, but also on potential synergistic or antagonistic interactions between compounds within the extract [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Extracts Characterization and In Vitro Evaluation of Potential Immunomodulatory Activities of the Moss Hypnum cupressiforme Hedw.

et al. 2020

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Recently, there has been an increasing interest in the chemistry and biological potential of mosses, since a large number of biologically active compounds have been found within these species. This study aimed at examining the chemical composition and immunomodulatory potential (antioxidant, antidiabetic, anti-neuroinflammatory/antineurodegenerative, and antitumor activities) of moss Hypnum cupressiforme Hedw. extracts. Corresponding extracts have been obtained applying Soxhlet extractor. The chemical characterization was performed using spectrophotometric assays and liquid chromatography–mass spectrometry (LC-MS). The extracts were analyzed for antioxidant activity and for inhibitory activities on α-glucosidase, α-amylase, acetylcholinesterase, and tyrosinase. Additionally, extracts were tested against four cell lines—MRC-5, BV2, HCT-116, and MDA-MB-231—for antitumor and anti-inflammatory activities. Chemical analysis of extracts revealed the presence of flavonoids, phenolic acids, and triterpenoids. Major compounds identified by LC-MS in H. cupressiforme were kaempferol and five phenolic acids: p-hydroxybenzoic, protocatechuic, p-coumaric, gallic, and caffeic acid. According to biochemical assays the investigated extracts exhibited significant immunomodulatory potential. Significant antiproliferative potential against MDA-MB-231 cells has been observed together with the promising anti-neuroinflammatory application. The obtained data suggest that moss H. cupressiforme is a valuable natural source of biologically active compounds with potential application in the pharmaceutical industry.

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Section: Introductionmentioning

confidence: 99%

Extracts Characterization and In Vitro Evaluation of Potential Immunomodulatory Activities of the Moss Hypnum cupressiforme Hedw.

et al. 2020

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“…Antioxidant enzymes protect cells against the oxidative stress induced by both internal and external unfavorable conditions. High level of these antioxidants present in liverworts and mosses can serve as a future source for medicinally and cosmetically significant compounds [20].…”

Section: Antioxidant Property In Bryophytesmentioning

confidence: 99%

Bryophytes: A Potential Source of Antioxidants

Gahtori¹,

Chaturvedi²

2020

Bryophytes

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A variety of degenerative diseases are caused by free radicals. Oxidative stress, the major cause of the diseases, is due to the imbalance between the free radicals and the antioxidants. To overcome this imbalance, the body needs antioxidants whether endogenously present or supplied from exogenous sources. Hence, the search of effective natural antioxidants is greatly needed to fight the onset of degenerative diseases and aging. Indeed, vascular plants are well-known sources of good and efficient natural antioxidants. Non-tracheophytes are however relatively unexplored. Interestingly, these atracheophytes are endowed with the remarkable property of desiccation tolerance which makes them unique in the plant kingdom. The property is attributed to its specialized structure and rich reservoir of phytochemicals. Therefore, there is a need to bioprospect this rich resource for antioxidants.

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“…Numerous studies concerning tissues of bryophytes have documented, among others, the presence of hydrocarbons and aromatic compounds (e.g., bibenzyls) along with polycyclic aromatic. Varied groups of organic compounds such as: flavonoids, including flavones (e.g., apigenin, luteolin), flavonols (e.g., kaempferol), isoflavones and other hydroxy flavonoids; terpenoids, including lipophilic mono-, sesqui-, and diterpenoids; glycosides: glycosides of three- and tetraoxygenated coumarins, orobol glycosides; lipids and fatty acids and other volatile constituents have been identified [ 22 – 29 ]. Therefore, well-expressed antibacterial, antifungal, antiviral activities have been demonstrated for a number of bryophytes.…”

Section: Introductionmentioning

confidence: 99%

“…Bryophytes exhibit antioxidant and UV photoprotective properties too. Due to the phenolic content, including flavonoids and hydroxycinnamic acids, they can reduce direct and indirect effects of damaging UV radiation penetrating their tissues [ 1 , 5 , 17 , 20 , 21 , 26 , 27 , 29 – 31 , 32 – 40 ]. Mosses and their extracts so far have found application, among others, in the treatment of: skin diseases and skin-associated problems; respiratory system diseases; and cardio vascular system diseases.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats

et al. 2021

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Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substances with high biological activity. Five species of mosses from a large urban ecosystem were identified for present study. In order to determine their biological potential, multifaceted studies were carried out, including: total phenolics content, antioxidant activity, antimicrobial and antifungal study, cytotoxicity evaluation, and scratch assay to assess pro-regenerative effect in the context of their possible use as the ingredients of biologically active cosmetics. Additionally, determination of individual phenolic compounds in selected extracts of the tested mosses was made. Research showed that Ceratodon purpureus and Dryptodon pulvinatus extracts had the greatest potential as antioxidants and antimicrobial activity. The cytotoxicity assessment indicated that the extracts from Dryptodon pulvinatus and Rhytidiadelphus squarossus exerted the strongest negative effect on mouse fibroblast line L929 viability at higher concentrations. While, the extract from Tortulla muralis best stimulated human foreskin fibroblast line HFF-1 proliferation and wound healing. The research on individual phenolic compounds content in the extracts tested indicated over 20 peaks on UPLC chromatograms. The conducted study has shown that mosses, especially so far unexplored species of open ecosystems, and e.g. epilytic habitats, may be a valuable source of biologically active substances and thus may constitute important medical and cosmetic possibilities.

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Total Phenol Content and Antioxidant Activity of Mosses From Yenice Forest (Ida Mountain)

Abstract: Recent pharmacological investigations of bryophytes

Cited by 17 publications

References 10 publications

Extracts Characterization and In Vitro Evaluation of Potential Immunomodulatory Activities of the Moss Hypnum cupressiforme Hedw.

Extracts Characterization and In Vitro Evaluation of Potential Immunomodulatory Activities of the Moss Hypnum cupressiforme Hedw.

Bryophytes: A Potential Source of Antioxidants

Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats

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