Total phenolic and flavonoids contents and &lt;i&gt;in vitro&lt;/i&gt; evaluation of antioxidant activity of several &lt;i&gt;Calendula officinalis&lt;/i&gt; (Marigold) extracts

Chroho, Mounia; Drioiche, Aziz; Saidi, Soukaina; Zair, Touriya; Bouissane, Latifa

doi:10.4081/jbr.2021.9680

Cited by 5 publications

(5 citation statements)

References 26 publications

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“…In epidemiological studies, fruits and vegetables in the diet have proven to protect against various chronic illnesses including cancer, cardiovascular disease, cataracts, and immunological dysfunction (Figure 8) [6,30]. Various phenolic and flavonoid constituents have been linked with natural protective benefits [31][32][33]. The biological actions of phenolics, which are powerful antioxidants and free radical scavengers, have been subject to several earlier investigations [34,35,28].…”

Section: Discussionmentioning

confidence: 99%

“…Hence, polyphenols protect against human diseases associated with oxidative stress, like coronary heart disease and cancer [28,31]. After studying the literature, it was found that major polyphenolic classes which have prominent effects as antioxidants, and other health benefits present in Alstonia scholaris, Tabernaemontana divaricata, Tagetes erecta [8,13,18,33]. Antioxidant activity evaluation revealed that Saraca asoca showed great antioxidant activity in eliminating hydroxyl radicals (Figure 9).…”

Section: Discussionmentioning

confidence: 99%

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Exploring Natural Medicinal Resources: Comparative Study on Antioxidant and Cytotoxicity Potential

2024

Curr Res Cmpl Alt Med

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Background: Plants have served as the foundation of traditional medicines. The myriad of compounds belonging to chemical classes found in plants have been associated with various therapeutic potential. Recent research reports showed that plant-derived phenolic compounds possess great antioxidant properties and exhibit cytotoxic potential as well. Southern Haryana has a rich diversity of plants many of which remained under-explored for their therapeutic properties. Objective: In the present study, selected widely growing plants in the region were evaluated for their antioxidant and cytotoxicity potential. Methods: The antioxidant activity was evaluated using (2,2-dyphenyl-1-picrylhydrazyl (DPPH) scavenging, ferric reducing antioxidant power (FRAP) assay, and cytotoxic potential was evaluated using (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) (MTT) assay. Results: Glycyrrhiza glabra showed maximum radical scavenging activity whereas Cinnamomum verum was found to have maximum antioxidant potential as estimated by FRAP assay i.e., range from 0.8 to 1 mg FSE/g DW. Tectona grandis has maximum phenolic content with a range of 30 to 35 ± 3.01 mg GAE/g DW). The maximum flavonoid content was found in the Saraca asoca. The highest antioxidant potential was shown by Fraxinus excelsior and Cinnamon verum. Conclusion: This study demonstrated that the widely growing plants could be a potential source of natural antioxidants and selected plants may further prove beneficial in targeting diseases associated with oxidative stress. Plants have the potential to be a long-term sustainable resource of bioactive chemicals. The present study also exhibited that the therapeutic potential of plants is highly reliant on the type of plant material used.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Exploring Natural Medicinal Resources: Comparative Study on Antioxidant and Cytotoxicity Potential

2024

Curr Res Cmpl Alt Med

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“…Among the interesting properties of essential oils, the antioxidant and antibacterial activities are highly appreciated since they might help to address two significant issues affecting human health, namely oxidative stress and antibiotic resistance [6]. In fact, they can act as natural antioxidants and antibiotics and substitute the synthetic ones that might be noxious and unhealthy [7]. The essential oils of plants are a complex combination of chemical components.…”

Section: Introductionmentioning

confidence: 99%

“…Among the species of this family, the genus Origanum and Thymus are widely known and highly appreciated in traditional medicine throughout the world. In Morocco, both the species are included in the most significant medicinal plants commonly used in traditional medicine and mostly studied for their several biological activities [7,10,11]. Known locally as "Zaâtre" for O. compactum and "Zaîtra" for T. zygis, they may be applied against a wide spectrum of pathologies and in industrial fields such as foods, pharmaceuticals, aromatherapy and perfumes [10][11][12][13][14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of Origanum compactum and Thymus zygis Essential Oils

Chroho,

Rouphael,

Petropoulos

et al. 2024

Antibiotics

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Essential oils are of great interest due to their potent pharmaceutical and biological activities. In this study, essential oils extracted from Origanum compactum and Thymus zygis originating from the Middle Atlas of Morocco were investigated. Their chemical compositions were analyzed using gas chromatography and mass spectrometry, while the assessment of the trapping power of the radical (DPPH: 1,1-diphenyl-2-picrylhydrazyl) and the reducing antioxidant potential of ferric ions (FRAP: Ferric Reducing Antioxidant Power) were performed in order to evaluate the antioxidant activity. Their antibacterial potency was tested against six bacterial strains through the disk diffusion method. The chromatography analyses of the extracted essential oils highlighted the presence of two main components, namely carvacrol at 75.70% in O. compactum and thymol at 40.67% in T. zygis. The antioxidant activity tests showed that both essential oils demonstrated a significant antioxidant activity comparable to the positive control (e.g., ascorbic acid). The antibacterial activity results showed a strong antimicrobial effect for both essential oils, compared to synthetic antibiotics. This study affirms the presence of bioactive components with interesting antioxidant and antibacterial activities in the essential oils extracted from Origanum compactum and Thymus zygis, which could find several applications in the food and pharmaceutical industries through the substitution of synthetic antioxidants and antibiotics.

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“…Various plant sections, such as leaves and flowers, have been stated to have therapeutic properties (3). The "Food and Drug Administration" (FDA) and t h e " F l a v o r s a n d E x t r a c t s M a n u f a c t u r e r s Association" (FEMA) have determined that the plant's components and dried flowers which are often used as spices are safe (4). According to the literature, C.officinalis has been widely studied for its various health benefits.…”

Section: Introductionmentioning

confidence: 99%

Effect of Calendula officinalis Linn in Oral health- A Review

NJ¹,

Ravikumar²,

Mahalaxmi³

et al. 2022

IJAM

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Calendula officinalis L., a member of the Asteraceae family, is often known as English Marigold or Pot Marigold. Marigold is an annual or perennial herb traditionally used to treat wounds, ulcers, herpes, scars, skin damage, frostbite, and blood purification. It is mainly used to treat disorders as an anti-diabetic, anti-ulcer, anti-inflammatory, and analgesic activity because of its numerous biological properties. This plant has a high concentration of medicinally active substances such as carotenoids, flavonoids, glycosides, steroids and sterols, quinines, volatile oil, and amino acids. The plant extract, as well as the pure compound derived from it, has been shown to have a variety of pharmacological properties, including anti-cytotoxic, hepatoprotective, and spasmolytic effects, among others. It is used to treat oral mucositis, angular cheilitis, periodontal bone loss, leukoplakia and also used as a root canal irrigant, intracanal medicament, and anti-plaque agent in dentistry. It also helps to heal and manage microbial plaque in gingivitis and periodontitis, boosting immunity. The most significant obstacle and concern is the lack of knowledge regarding the effects of C.officinalis on oral tissues, their mechanisms of action, and their adverse effects. Hence, this review has explored the various medicinal properties of C.officinalis useful in the multiple fields of dentistry.

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Total phenolic and flavonoids contents and <i>in vitro</i> evaluation of antioxidant activity of several <i>Calendula officinalis</i> (Marigold) extracts

Cited by 5 publications

References 26 publications

Exploring Natural Medicinal Resources: Comparative Study on Antioxidant and Cytotoxicity Potential

Exploring Natural Medicinal Resources: Comparative Study on Antioxidant and Cytotoxicity Potential

Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of Origanum compactum and Thymus zygis Essential Oils

Effect of Calendula officinalis Linn in Oral health- A Review

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