Coconut protein residue from production of coconut oil with extracted Curcuma longa has high antioxidant as curcuminoids, and high protein which are needed for growth performance and survival rate of Juvenile red claw crayfish (Cherax quadricarinatus). The objective of this work was to study the effects of coconut protein residue from production of coconut oil with extracted Curcuma longa in feed to growth performance and survival rate of Juvenile red claw crayfish. The experiment was carried out using plastic bucket systems with three treatment conditions: T1 used pellet (control); T2 used cream protein from virgin coconut oil (VCO); T3 used cream protein from coconut oil with extracted Curcuma longa (COC), respectively. Feed with cream protein from COC and VCO has significant effect on weight gain and feed conversion ratio (FCR) of Juvenile red claw crayfish when compared to Juvenile red claw crayfish in the control diet. FCR in the control group was significantly (p<0.05) higher than those of the treated groups. Weight gain was highest in the T3. Survival rate of every treatment was 100%. The result indicated that the cream protein from COC with high protein and high antioxidant is a potential additive in the Juvenile red claw crayfish diet.