Total Phenolic Content, Antioxidant Capacity and Antifungal Activity of Extracts of Carthamus tenuis and Cephalaria joppensis

Azab, Abdullatif

doi:10.17628/ecb.2018.7.156-161

Cited by 8 publications

(5 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The antioxidant activity of a C. jopponsis aqueous, ethanolic and ethyl acetate extracts were evaluated in vitro (phosphomolybdenum method) [ 38 ]. The studied extracts showed antioxidant activity ranging from 20.7 to 41.1 mg of ascorbic acid/g dry extract.…”

Section: Phenolic Compounds In the Cephalaria Speciesmentioning

confidence: 99%

“…Moreover, they are used in veterinary medicine and agriculture, as a wool dye and as an additive to bread [ 34 , 35 ]. Literature studies have shown that the Cephalaria species contain flavonoids [ 17 , 36 , 37 ], triterpenoid saponins [ 36 , 38 , 39 , 40 ], iridoids [ 36 , 37 , 40 ], alkaloids [ 37 , 41 , 42 , 43 ], lignans [ 37 , 44 ], fatty acids [ 45 , 46 ], that exhibit antioxidant, antimicrobial, cytotoxic, hemolytic, and immunomodulating activities [ 3 , 18 , 27 , 31 , 41 , 42 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Chrząszcz

Krzemińska

Skowronek

et al. 2021

Plants

View full text Add to dashboard Cite

The genus Cephalaria, belonging to the Caprifoliaceae family, is a rich source of interesting secondary metabolites, including mainly saponins which display a variety of biological activities, such as immunomodulatory, antimicrobial and hemolytic effects. Besides these compounds, flavonoids and phenolic acids were identified in Cephalaria species. Cephalaria is employed in traditional medicine e.g., to cure cardiac and lung diseases, rheumatism, and regulate menstruation. In this review we focus on the phenolic compound composition and antioxidative activity of Cephalaria species. The antioxidant effect can be explained by flavonoids present in all parts of these plants. However, future efforts should concentrate more on in vitro and in vivo studies and also on clinical trials in order to confirm the possibility of using these plants as natural antioxidants for the pharmacology, food or cosmetic industries.

show abstract

Section: Phenolic Compounds In the Cephalaria Speciesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Chrząszcz

Krzemińska

Skowronek

et al. 2021

Plants

View full text Add to dashboard Cite

show abstract

“…Moreover, the state of knowledge of the antioxidant activity of Cephalaria species is fragmentary. Azab [52] found that aqueous, ethanolic and ethyl acetate extracts of the aerial parts of C. jopponsis possess high antioxidant activity (41.1, 30.1 and 20.7 mg of ascorbic acid g −1 of dry extract, respectively).…”

Section: Antioxidant Activitymentioning

confidence: 99%

Extracts from Cephalaria Uralensis (Murray) Roem. & Schult. and Cephalaria Gigantea (Ledeb.) Bobrov as Potential Agents for Treatment of Acne Vulgaris: Chemical Characterization and In Vitro Biological Evaluation

et al. 2020

View full text Add to dashboard Cite

The aim of this study was to compare the chemical composition, as well as antioxidant, anti-inflammatory, antiacne, and cytotoxic activites of various extracts of Cephalaria gigantea and C. uralensis. It is worth underlining that we are the first to characterize the composition and evaluate the biological properties of extracts from Cephalaria gigantea and C. uralensis. Thus, the LC-DAD-MS3 analysis revealed the presence of 41 natural products in studied extracts. The 5-O-caffeoylquinic acid, isoorinetin, and swertiajaponin were the main detected compounds. Among the tested samples, ethanol extract of the aerial parts of C. uralensis (CUE) possessed the most suitable biological properties. It exhibited moderate ability to scavenge free radicals and good capacity to inhibit cyclooxygenase-1, as well as cyclooxygenase-2. Moreover, CUE possessed moderate antibacterial activity against all tested bacterial strains (S. aureus, S. epidermidis, and P. acnes), and importantly, it was non-toxic towards normal skin fibroblasts. Taking into account the value of calculated therapeutic index (>10), it is worth noting that CUE can be subjected to in vivo study. Thus, CUE constitutes a very promising antiacne agent.

show abstract

“…Majority of these compounds were polyphenolic compounds that show a very strong antioxidant activity. 5 Caffeic acid, quercetin and luteolin were found to be of the major composition of the total phenolic content in C. tenuis extract, each one of them was found to have an anticancer potential on different cancer cell lines. 11 The screening of plant extracts has been of great interest to scientists in the search for new drugs for effective treatment of several diseases.…”

Section: Introductionmentioning

confidence: 98%

“…3,4 The plant showed in few studies an anti-bacterial, antifungal, antioxidant and anti-inflammatory activities. [4][5][6] It was found that one of its compounds showed an immunesuppresive activity. 7 Oxidative stress is one of the factors that found to induce different types of cancer, so in many studies, the antioxidant activity for different kinds of plants showed a strong impact on the progression of cancer.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Carthamus tenuis Extracts on the Cell Proliferation of Different Tumor Cell Lines

Shawagfeh¹

2020

View full text Add to dashboard Cite

Background: Carthamus tenuis is one of the medicinal plants that was used traditionally to treat skin diseases, hemorrhoids, abortion, infertility. It also showed an immunosuppressive role as well as antifungal, antibacterial, anti-inflammatory activity. Although this plant is widespread, there are few studies about its medical applications. Objectives: This study was done to explore the anticancer activity of this plant. Materials and Methods: The aerial parts of the plant were dried, grinded and extracted with hexane, ethyl acetate, and methanol. The extracts were applied in different concentrations to cell cultures of breast (MCF-7), colon (HT-29), prostate (PC-3) and colorectal (CaCo-2) cell lines and fibroblast (MRC-5) was used as a control. The anticancer activity was evaluated by 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium (MTT) reduction assay that was measured by spectrophotometer. Results: The results showed that methanol extract significantly (p<0.05) have the highest inhibitory activity on MCF-7, HT-29, PC-3, and CaCo-2 with IC50; (25.52 µg/ml), (17.37 µg/ml), (25.77 µg/ml), (24.49 µg/ml), respectively. Followed by ethyl acetate extract that moderately inhibit cell growth of PC-3 and CaCo-2 with IC50; (28.99 µg/ml) and (21.45 µg/ml), respectively. n-hexane extract showed no significant inhibitory effect on all cell lines; IC50 (125.52-152.34 µg/ml) when compared to Tamoxifen drug activity as a positive control. Conclusion: Results of this study showed the anticancer activity of the plant extracts in four different kinds of cancers that need further study.

show abstract

Total Phenolic Content, Antioxidant Capacity and Antifungal Activity of Extracts of Carthamus tenuis and Cephalaria joppensis

Cited by 8 publications

References 38 publications

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Extracts from Cephalaria Uralensis (Murray) Roem. & Schult. and Cephalaria Gigantea (Ledeb.) Bobrov as Potential Agents for Treatment of Acne Vulgaris: Chemical Characterization and In Vitro Biological Evaluation

The Effect of Carthamus tenuis Extracts on the Cell Proliferation of Different Tumor Cell Lines

Contact Info

Product

Resources

About