Total removal of a primary intracranial squamous cell carcinoma invading the brain stem

Ogata, Nobuyoshi; Jochum, Wolfram; Aguzzi, Adriano; Fournier, Jean Yves Alain; Yonekawa, Yasuhiro

doi:10.1016/s0090-3019(96)00222-4

Cited by 10 publications

(5 citation statements)

References 5 publications

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“…She underwent radiation and chemotherapy but died of disease 2 years after her initial surgery. There have been approximately 50 cases of malignant intracranial epidermoid tumors reported in the literature 14 . They are encapsulated tumors and, as shown in our series and others, complete resection can be achieved 14 .…”

Section: Discussionsupporting

confidence: 71%

Neurotologic Management of Intracranial Epidermoid Tumors

et al. 2005

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Section: Discussionsupporting

confidence: 71%

Neurotologic Management of Intracranial Epidermoid Tumors

et al. 2005

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“…1,2,9,11,14) Nineteen of 37 cases of primary ovarian squamous cell carcinoma were associated with dermoid cysts. 15) However, malignant transformation of intracranial dermoid cysts, 4,8,12) intraspinal dermoid cyst, 7) or intravertebral dermoid cyst 6) are more rare.…”

Section: Discussionmentioning

confidence: 99%

“…Primary intracranial squamous cell carcinoma is extremely rare, and usually arises in an epidermoid cyst 1,2,9,11,14) and only rarely in a dermoid cyst. 4,8,12) We report a case of intracranial squamous cell carcinoma arising in a dermoid cyst.…”

Section: Introductionmentioning

confidence: 99%

Squamous Cell Carcinoma Arising in an Intracranial Dermoid Cyst. Case Report.

Tsugu

Fukushima

Hayashi

et al. 2001

Neurol. Med. Chir.(Tokyo)

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A 47-year-old male presented with headache. Magnetic resonance imaging revealed an enhanced mass lesion in the cerebellar vermis and left cerebellar hemisphere and in the cisterna magna. Gross total removal of the tumor was performed. Histological examination demonstrated squamous cell carcinoma in the dermoid cyst. The patient subsequently received localized radiation therapy of total 55 Gy. He has been without tumor recurrence for 6 years since the surgery. We recommend local radiation therapy over 50 Gy following surgery.

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“…Transformation of an epidermoid cyst has been described in the vast majority of such cases [19, 20]. There have been only few case reports of de novo intra-cranial SCC [21, 22] and malignant transformation of other non-neoplastic epithelial cysts. Those cysts include most commonly dermoid cysts, or more rarely epithelial cysts, neuroepithelial cysts, endodermal cysts and a craniopharyngioma [1, 3, 23–26].…”

Section: Discussionmentioning

confidence: 99%

Non-metastatic squamous cell carcinoma within a Rathke’s cleft cyst

et al. 2015

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Primary intracranial and sellar squamous cell carcinoma is an extremely rare entity, usually caused by malignant transformation of epidermoid cysts, or very rarely other non-malignant epithelial cysts. Malignant transformation of a Rathke’s cleft cyst has never been described. We present a 49-year-old male patient who presented with a 3-month history of progressive frontotemporal headaches. Imaging revealed a 1.2 cm cystic pituitary mass consistent with a hemorrhagic Rathke’s cleft cyst. The patient underwent trans-sphenoidal resection of the pituitary cyst, and pathologic analysis revealed a squamous cell carcinoma lining a Rathke’s cleft cyst. Extensive imaging and otorhinolaryngologic evaluation revealed no primary source for metastasis. We feel this represents the first case of a patient with a pituitary lesion in which presentation and MRI imaging were consistent with Rathke’s cleft cyst, yet histology revealed squamous cell carcinoma in situ.

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Total removal of a primary intracranial squamous cell carcinoma invading the brain stem

Cited by 10 publications

References 5 publications

Neurotologic Management of Intracranial Epidermoid Tumors

Neurotologic Management of Intracranial Epidermoid Tumors

Squamous Cell Carcinoma Arising in an Intracranial Dermoid Cyst. Case Report.

Non-metastatic squamous cell carcinoma within a Rathke’s cleft cyst

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