Total Syntheses of Carbazole Alkaloids Lansine F and Clauemarazole D

Guo, Yanqin; Huang, He; Zhang, Tiantian; Qi, Shuang; Liu, Yizhen; Li, Mengyang; Wang, Penghao; Song, Chuanjun; Chang, Junbiao

doi:10.1002/ajoc.201600311

Cited by 4 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus far, researchers have performed preliminary studies of the catalytic function of carbon material in CH 4 –CO 2 re-forming. , The groups have researched CH 4 –CO 2 re-forming over semicokes that is activated with H 2 O 2 at high temperatures and high pressures. − The results show that semicoke has a significant catalytic function for the re-forming reaction. In addition, the surface area of semicokes and the content of oxygen groups both increased significantly after activation.…”

Section: Introductionmentioning

confidence: 99%

Activity Enhancement of Semicokes by Ammonia Activated at High Temperatures and High Pressures for Carbon Dioxide Re-forming of Methane

et al. 2014

View full text Add to dashboard Cite

In a WHF-08-type reactor, three kinds of semicokes (Hongce lignite semicokes, Shenmu bituminous coal semicokes, and Jincheng anthracite semicokes) were activated with ammonia at high temperatures and high pressures. Results showed that the catalytic activity of the semicokes was significantly enhanced after activation. It was observed that the conversions of methane and carbon dioxide increased with increases in the concentration of ammonia and the activation temperature and increased and then stabilized as the activation time increased. It was also observed that the activation pressure had relatively weaker effects on the re-forming reaction and the optimal conditions were as follows: 8% ammonia, 300 °C, 6 MPa, and 3 h. The surface structures of semicokes before and after activation were characterized. The results showed that the content of -NO 2 , -NH 2 , -CN, and other basic groups increased while the content of acidic groups decreased after activation, and the TNB of the three kinds of semicokes improved to 0.373, 0.325, and 0.249 mmol g −1 , respectively, which increased the number of active centers of semicoke and promoted the adsorption of methane and carbon dioxide on the surface of semicokes.

show abstract

Section: Introductionmentioning

confidence: 99%

Activity Enhancement of Semicokes by Ammonia Activated at High Temperatures and High Pressures for Carbon Dioxide Re-forming of Methane

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Previously, our group completed the synthesis of a series of nitrogen-containing heterocycles. − On this basis, we conducted preliminary studies with 1-methyl-3,4-dihydroisoquinoline and methyl 2-bromobenzoate under palladium-catalyzed conditions. Gratifyingly, we can synthesize the protoberberine derivatives in one pot.…”

mentioning

confidence: 99%

Construction of a Protoberberine Alkaloid Skeleton via the Palladium-Catalyzed α-Arylation–Amide Formation Cascade

Nie

Duan

et al. 2021

Org. Lett.

Self Cite

View full text Add to dashboard Cite

In this work, we report the strategy of one-pot synthesis of protoberberine alkaloid derivatives via palladiumcatalyzed cascade α-arylation and cyclization, which can afford the target molecules in moderate to excellent isolated yields using commercially available raw materials under solvent-free conditions. This protocol provides an efficient and convenient path to multisubstituted protoberberine derivatives. In addition, it can directly afford natural alkaloids.

show abstract

“…However, multistep functional group transformations under controlled reaction conditions were required. As part of our continued interest in natural product synthesis, we herein report a concise total synthesis of (+)-aspidospermidine featuring a one-pot reductive amination–carbonyl reduction–dehydration–intramolecular conjugate addition cascade to build the cis D-ring under mild reaction conditions. Such a strategy has never been applied previously in the synthesis of Aspidosperma alkaloids.…”

mentioning

confidence: 99%

Total Synthesis of (+)-Aspidospermidine

Huang

Zhao

et al. 2019

Org. Lett.

Self Cite

View full text Add to dashboard Cite

A facile asymmetric total synthesis of (+)-aspidospermidine has been developed, which is accomplished in 11 steps in an overall yield of 9.6%. Key steps involve a palladium-catalyzed enantioselective decarboxylative allylation to install the quaternary carbon stereocenter and a highly efficient reductive amination−carbonyl reduction−dehydration−intramolecular conjugate addition cascade to build the cis D-ring.

show abstract

Total Syntheses of Carbazole Alkaloids Lansine F and Clauemarazole D

Cited by 4 publications

References 10 publications

Activity Enhancement of Semicokes by Ammonia Activated at High Temperatures and High Pressures for Carbon Dioxide Re-forming of Methane

Activity Enhancement of Semicokes by Ammonia Activated at High Temperatures and High Pressures for Carbon Dioxide Re-forming of Methane

Construction of a Protoberberine Alkaloid Skeleton via the Palladium-Catalyzed α-Arylation–Amide Formation Cascade

Total Synthesis of (+)-Aspidospermidine

Contact Info

Product

Resources

About