2023
DOI: 10.1039/d3cc01997g
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Total synthesis of applanatumol A

Abstract: The first total synthesis of applanatumol A has been achieved in a highly stereocontrolled manner. The synthetic method includes assembly of the contiguous chiral centers by convergent Fráter-Seebach alkylation, construction...

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Cited by 4 publications
(1 citation statement)
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“…The highly stereocontrolled total synthesis of applanatumol A [2a] was reported by Ito's group. [74] The synthetic features are an intramolecular aldol reaction to achieve the seven-membered cyclization and a tandem cyclization to form the tetracyclic core skeleton (Scheme 15).…”
Section: Ito's Work (2023)mentioning
confidence: 99%
“…The highly stereocontrolled total synthesis of applanatumol A [2a] was reported by Ito's group. [74] The synthetic features are an intramolecular aldol reaction to achieve the seven-membered cyclization and a tandem cyclization to form the tetracyclic core skeleton (Scheme 15).…”
Section: Ito's Work (2023)mentioning
confidence: 99%