Molecules
 2020
DOI: 10.3390/molecules25214903
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Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization

Sunhwa Park
1
,
Kye Jung Shin
2
,
Jae Hong Seo
3

Abstract: Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation.

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