Total synthesis of erythronolide B. 1. Skeleton assembly in (C9C13) + (C7C8) + (C1C6) sequence.

An improved protocol for aerobic oxidation of acetals to esters catalyzed by N-hydroxy phthalimide (NHPI) and lipophilic Co(II) complexes

“…Although, there is a limited number of procedures on the oxidation of cyclic acetals by H 2 O 2 , t-BuOOH, and stoichiometric oxidizing agents [3][4][5][6][7][8][9][10][11][12][13][14], in particular, their oxidations with O 2 via a radical process is rarely reported [15]. Thus, we decided to expand the domain of this new protocol over the oxidation of various types of cyclic acetals.…”

“…This transformation was traditionally carried out using stoichiometric Cr salts [3], peracetic acid [4], DDQ [5], sodium perborate [6], halogen-based reagents [7], oxone [8], VO(OAc) 2 [9], etc. However, many of these protocols lead to expensive processes and toxic by-product.…”

Efficient Aerobic Oxidation of Acetals to Esters Catalyzed byN-Hydroxy phthalimide (NHPI) and Co(II) under Mild Conditions

“…1 Moreover, direct oxidation of both acetals and also aldehydes to the corresponding esters is an interesting transformation in organic chemistry as testified by a large number of reagents applied in this reaction. 2 This transformation was traditionally carried out using stoichiometric amounts or Chromium salts, 3 peracetic acid, 4 DDQ, 5 sodium perborate, 6 halogen-based reagents, 7 Oxone, 8 VO(OAc) 2 , 9 etc. However, almost the entirety of these protocols leads to expensive processes and the formation of toxic by-products.…”

New Derivatives of Levoglucosan by Tandem Epoxide Allyl Alcohol Rearrangement‐Cuprate Cross‐Coupling

“…[13][14][15][16][17] In more recent times, levoglucosan (1) was used to prepare a variety of advanced chiral building blocks. [18][19][20][21][22][23] However, the rigid 1 C 4 conformation of 1 and the shielding by the 1,6-anhydro bridge also limits the stereochemical diversity. Only a comparatively small number of well defined isomeric branched methyl derivatives of 1 are readily available.…”