ChemistrySelect
 2023
DOI: 10.1002/slct.202300352
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Total Synthesis of Okaspirodiol

Madasu Madhu
1
,
Debendra K. Mohapatra
2

Abstract: The asymmetric total synthesis of okaspirodiol was achieved following Sharpless asymmetric epoxidation, Gilman reaction, Wittig reaction, Horner–Wadsworth–Emmons olefination, and coupling of alkyne with the aldehyde, and acid‐catalyzed spiroketalization as key reactions.

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