Totally self-contained intracardiac pacemaker

Spickler, J.W.; Rasor, N. S.; Kezdi, Paul; Misra, Satyajeet; Robins, K.; Leboeuf, Charles

doi:10.1016/s0022-0736(70)80059-0

Cited by 105 publications

(44 citation statements)

References 8 publications

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“…3 While the concept of leadless pacing was first proposed in 1970, not until 2012, with implantation of the St. Jude leadless pacemaker, did practical application of this concept come to fruition. 4,5 …”

Section: Eachmentioning

confidence: 99%

Leadless Cardiac Pacemaker Therapy. An Overview for the Hospitalist

Weachter¹

2018

Am J Hosp Med

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Section: Eachmentioning

confidence: 99%

Leadless Cardiac Pacemaker Therapy. An Overview for the Hospitalist

Weachter¹

2018

Am J Hosp Med

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“…[25] So, the size of the pacemaker should be compatible with intravenous introduction, that is, its diameter should be around 6 mm. However, most of the designs proposed so far [20][21][22]12] have dimensions more than that of intravenous cavity hence very impractical from pacemaker design point of view.…”

Section: Doi: 101002/gch2201700084mentioning

confidence: 99%

A Comparative Numerical Study on Piezoelectric Energy Harvester for Self‐Powered Pacemaker Application

et al. 2017

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The potential application of this energy harvesting has been recognized in the form of the replacement of batteries of the pacemakers. Since the Ni-Cd or Li-ion batteries used for pacemakers have finite life span [15] and hence these require replacement after a certain period. To overcome this drawback, researchers have been exploring methods where an energy harvester could scavenge energy from human body and power the pacemaker.Goto et al. [16] carried out the pioneering work in the field of powering leadless pacemakers. A kinetic watch energy generating system was employed on a dog's heart and 13 µJ of energy per heartbeat was successfully achieved. Tashiro et al. conducted an experiment where pacemaker was powered by harvesting enough energy from the motion of canine heart. [17] However, the design proposed by them is practically impossible to be placed inside the thoracic cavity of the laboratory animal. Recently, Karami and Inman [12] have proposed zig-zag structures to achieve lower frequencies with piezoceramics to power pacemaker implanted in chest. Heart beat acceleration was used in this study for actuating the harvester but the size of harvester is too large to be inserted into intravenous cavity. Zurbuchen et al. recently conducted an in vivo study on pig's heart for 30 min. [18] Their study aimed at demonstration of battery and leadless cardiac pacing by using energy harvesting mechanism derived from Swiss wristwatch. It was shown that the mechanism generated sufficient electrical power (<10 µW) to meet out the demand of a typical modern pacemaker. [19] A number of researchers have carried out research in this field where piezoelectric energy harvester has been employed to power pacemaker. An exhaustive literature review regarding piezoelectric energy harvesting for pacemaker application along with limitations has been presented in Table 1.The size of miniaturized leadless pacemaker should be such that it can be directly placed inside the heart. [25] So, the size of the pacemaker should be compatible with intravenous introduction, that is, its diameter should be around 6 mm. However, most of the designs proposed so far [20][21][22]12] have dimensions more than that of intravenous cavity hence very impractical from pacemaker design point of view. To the best of authors' knowledge, there is hardly any literature available dealing with the design and study of the energy harvesting systems

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“…The first totally self-contained leadless pacemaker system was proposed by Spickler in 1970 [13], using a device powered by mercury-zinc and nuclear power with pacing electrodes being directly placed on the pacemaker capsule and implanted with a catheter-based system inserted through the femoral vein. It was successfully tested in animals but limitations in battery technology and electronics prevented progression of the system to human trials.…”

Section: Introductionmentioning

confidence: 99%

Leadless Pacemakers: practice and promise in congenital heart disease

Clarke

Zaidi

Clarke

2017

J Congenit Heart Dis

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The development of the implantable cardiac pacemaker nearly 60 years ago represented a paradigm shift in the control of potentially lethal heart rhythms and has revolutionized the lives of those at risk of sudden death from bradycardia. Subsequent technological developments have resulted in devices that offer additional benefits to patients, including defibrillation and resychronisation therapy. Previously, Cardiac Implantable Electronic Devices (CIEDs) relied on leads, either transvenous or epicardial, to transmit electronic impulses to the heart. The potential value of self-contained leadless intracardiac pacemaker devices has long be recognised with their potential to avoid intrinsic problems with traditional CIEDs, particularly device-related infection and lead failure. Two leadless devices have been introduced since 2012 which may offer a safe, long term alternative to leaded CIEDs with greater patient acceptability and greater flexibility, particularly for congenital heart disease patients where venous access problems may otherwise limit access to traditional transvenous systems. Here we examine the development of leadless pacemakers, the current state of affairs in clinical practice, and key considerations for future developments, with a focus on the usage of such devices in the setting of congenital heart disease.

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Totally self-contained intracardiac pacemaker

Cited by 105 publications

References 8 publications

Leadless Cardiac Pacemaker Therapy. An Overview for the Hospitalist

Leadless Cardiac Pacemaker Therapy. An Overview for the Hospitalist

A Comparative Numerical Study on Piezoelectric Energy Harvester for Self‐Powered Pacemaker Application

Leadless Pacemakers: practice and promise in congenital heart disease

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