“Tourism for all” is based on three main aspects: accessible tourism, sustainable tourism and social tourism. Accessibility is an essential part of responsible and sustainable tourism. A sizable segment of the population comprises people who have a type of disability or people who are older and, as a result of age, experience diminished physical and/or mental abilities. The aim of this study is to analyze whether the mobile applications and websites of Portuguese and Spanish Destination Management Organizations (DMOs) are accessible. For this purpose, accessible destinations listed by the Tur4all project were taken as a sample for a quantitative exploratory study. Several tools related to accessibility were used to determine their level of compliance with the Web Content Accessibility Guidelines (WCAG) 2.1. The results reveal that the percentage of non-compliance with accessibility criteria is very high in DMOs in Portugal and especially in Spain. In conclusion, tourism for all is important, including its digital tools. The practical implications include guidance on accessibility for institutions and companies, as well as a need to raise awareness of its importance in the tourism sector. This is the only study that analyzes the accessibility of both apps and websites of the same institution according to the requirements in WCAG 2.1.