“…Rapid response, an early substantial decline in symptomatology within the first 1 – 4 weeks of treatment found in approximately one third of research subjects, has been described in a number of treatments for depression (Ilardi & Craighead, 1994; Tang & DeRubeis, 1999), alcohol use disorders (Breslin, Sobell, Sobell, Buchan, & Cunningham, 1997), panic disorder (Penava, Otto, Maki, & Pollack, 1998), irritable bowel syndrome (Lackner et al, 2010), bulimia (BN; Fairburn, Agras, Walsh, Wilson, & Stice, 2004; Jones, Peveler, Hope, & Fairburn, 1993; Marrone, Mitchell, Crosby, Wonderlich, & Jollie-Trottier, 2009), and, more recently, binge eating disorder (BED; Grilo, Masheb, & Wilson, 2006; Grilo & Masheb, 2007; Masheb & Grilo, 2007; Zunker et al, 2010). There is no accepted explanation as to why some persons have an early substantive treatment response and not others.…”