Based on the findings from a recent study by the authors which examined factors affecting diffusion of photovoltaics (PV), while comprehensively considering the local PV and construction industry as well as characteristics of the built environment, this paper proposes a holistic strategy for PV implementation into Singapore’s built environment. It consists of (1) a multilevel mechanism framework, encompassing eleven mechanism categories of instruments and activities and (2) a general design framework including design principles, general project instructions and the main design guidelines. Relying on a survey conducted among PV experts on established mechanisms, the present study suggests that building codes (e.g., fire safety, structural safety, etc.) and initiatives and incentives related to PV/building-integrated photovoltaics (BIPV) should be the highest priority for authorities, followed by assessment of BIPV/PV properties, working toward social acceptance, conducting research projects and information exchange, and education and training activities. Considering all three pillars of sustainability, the design framework is based on the following interrelated design principles: (1) compatibility and coherence with the local context, (2) technical soundness, (3) economic viability, (4) user-centered design, (5) connecting with community and socio-cultural context, and (6) adaptability and flexibility. Despite Singapore’s scarcity of land, the established design guidelines cover a wide spectrum of solutions, including PV integration into both buildings and non-building structures. The synthesis of the two interconnected and inseparable frameworks aims to create an environment conducive to long-term widespread PV integration and stimulate the deployment of BIPV, which should help Singapore and other cities reduce their dependency on imported fossil fuels, while also making them more livable and enjoyable.