The aim of this paper is to develop the educational domain management knowledge content identification and knowledge updating method, based on formal descriptions of enterprise management information interactions. This is very important because the progress of modern science leads to the emergence of new factual or conceptual knowledge. There is a need for proper methods that allow, first, to study and make decisions regarding the relevance of the content, and then take practical steps on the content and possibly of the corresponding structure adaptation. The authors suggest a systematic solution for this problem. The hierarchical Detailed Value Chain Model and Elementary Management Cycle model of educational domain knowledge content identification and updating is formally described, computerized process measures are proposed. The paper provides a method for updating the knowledge of the analyzed domain, referred to as "enterprise domain", based on enterprise modelling in terms of management information interactions. A method, whose formal DVCM and EMC descriptions are provided in BPMN notation, was designed, allowing to develop a two-level (granular) model for describing knowledge of educational domain management information interactions. In implementing this model and its algorithms in technological terms, a subsystem of enterprise knowledge has been created in a knowledge-based CASE system (computerized knowledge-based IS engineering), performing the function of a domain knowledge database.