Towards miniaturized electrochemical sensors for monitoring of polychlorinated biphenyls

Abstract

Pollution of our environment as a result of industrialization and other human activities is a growing concern due to the harmful effects of most chemicals that are released into the environment. Of particular interest are the persistent organic pollutants (POPs) that are reported to be toxic and build up in the environment due to their persistence. Among the POPs are polychlorinated biphenyls (PCBs), which were widely used in the past in various applications ranging from additives in pesticides to dielectric fluids in electrical equipment. As a way of protecting the one health trilogy (environment, human and animal health), their determination in the environment is a paramount call that has seen researchers continue to provide advanced technologies towards achieving this goal. These technologies involve the conventional gold standard gas chromatography systems coupled to sensitive detectors that can detect trace level concentrations. They have come in handy in monitoring of PCBs but their application for routing monitoring may not be sustainable because of the cost of operation associated with them and the need for experts to run the equipment. As a result, there is need for affordable systems that are still able to achieve the required sensitivity for routine monitoring and real-time data acquisition. Sensor systems fit very well in this category since they can be miniaturized for affordability and portray many other desirable features. PCBs as environmentally relevant environmental pollutants have received minimal attention with regards to sensor development and this review highlights the efforts that have been made so far. It provides in-depth discussions on electrochemical sensors and the various modifications that have been employed to date to achieve detection of PCBs at low concentrations as well as the future prospects in remote and routine monitoring.

Emerging Trends of Immunosensors Development for Detection of Food Toxins

“…Potentiometric, amperometric, and conductimetric electrochemical techniques can all be used for analytical purposes. Nevertheless, due to their high sensitivity, affordability, and potential for instrument miniaturization, amperometric detection systems have been shown to be the most effective method for building immunosensors (Baranwal et al, 2022;Ndunda & Mwanza, 2023). Amperometric detection typically uses a three-electrode system, although in many cases, this is reduced to two electrodes in practice.…”