Towards responsible animal research

Matthiessen, Line; Lucaroni, Beatrice; Sachez, Elena

doi:10.1038/sj.embor.embor745

Cited by 23 publications

(19 citation statements)

References 3 publications

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“…A escolha dos delineamentos experimentais deve selecionar aqueles que utilizam menor número de animais, que envolvem menor grau de sensibilidade neurofisiológica, ou seja, causam menor dor, sofrimento, estresse e prejuízos duradouros 7 .…”

Section: Por Que Utilizar Animais Em Pesquisa?unclassified

“…Embora sejam evidentes os benefícios desse tipo de experimentação, a questão é, como proteger os animais e evitar sua utilização em experimentos desnecessários, e, finalmente, como aliviar os sofrimentos sem comprometer as respostas obtidas nos ensaios. Este problema permanece válido e controverso para a ciência, a sociedade e a polí-tica 7 .…”

Section: Debates éTicosunclassified

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Experimentação animal: ética e legislação brasileira

2008

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Este artigo trata da experimentação animal sob os pontos de vista da ética e da política, fazendo uma abordagem histórica do tema no cenário legislativo brasileiro. Os animais de laboratório desempenharam um papel decisivo para o desenvolvimento da ciência e continuam tendo um papel essencial na pesquisa biomédica, no entanto, sua utilização sempre despertou manifestação de diferentes naturezas. Apesar de as primeiras incursões na pesquisa experimental terem sido iniciadas há, pelo menos, quatro séculos, é incipiente o estabelecimento de normas que regulamentem a utilização de animais na América Latina. No Brasil, embora não haja uma lei específica em relação a essa utilização, algumas iniciativas já foram tomadas. As discussões sobre este tema continuam ocorrendo, contudo, a demora para definir uma lei que regulamente o uso de animais em pesquisa tem dificultado a padronização de procedimentos necessários à sistematização dos conhecimentos desenvolvidos no País. Termos de indexação: Ética. Experimentação animal. Legislação. A B S T R A C T This article covers animal experimentation under the viewpoint of ethics and politics, and does a historical review of the theme in the Brazilian legislative scenario. Laboratory animals play a decisive role in the development

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Section: Por Que Utilizar Animais Em Pesquisa?unclassified

Section: Debates éTicosunclassified

Experimentação animal: ética e legislação brasileira

2008

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“…Drugs are then applied, the tubes removed and the number of cells defined. This system has raised the amount of data that can be collected per animal in some investigations and has, therefore, decreased the number of mice used [5][6][7][8][9][10]. Although animals cannot yet be replaced entirely, it is essential that researchers maximize reduction and refinement.…”

Section: Introductionmentioning

confidence: 99%

“…No honest scientist desires to use animals or induce them unnecessary suffering if it can be bypassed, and therefore scientists admit controls on the use of animals in research. More frequently, the bioscience community believes that animals should be used for analysis only within an ethical frame [5][6][7]. The Three Rs (3Rs) in connection with science are leading systems for more ethical use of animals in experimentation.…”

Section: Introductionmentioning

confidence: 99%

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Ethical to using Rats in the Scientific Researches

Hamouda¹

2018

PPIJ

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Practical anatomy classes: An alternative to improve the learning of middle school students

Guimarães

Valério-Gomes

Araújo³

et al. 2023

Anatomical Sciences Ed

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Anatomy is the branch discipline focused on studying organisms' physical structures and parts. Although technological advances are broadening the anatomy study, the practices of prosection and dissection of human cadavers and animals remain a primary teaching method. Despite the large body of research supporting its benefits, in some countries, cadaveric prosection and dissection of vertebrate animals in secondary education have been banned. In the current study, to prevent a lack of access to anatomical sciences education, the use of plastinated biological specimens was proposed for teaching practical biology in middle and high schools. The study was conducted in the 2014 academic year. Eighty‐seven middle school students participated in the experiment. Groups consisted of: (i) theoretical classes only; (ii) theoretical class plus prosection with fresh specimens class; (iii) theoretical class plus expository with plastinated specimens classes. A post‐test grade method was used to assess the impact of such tasks on the learning experience of each group. An ANOVA test and multiple regression model were used to analyze the effects of the variables of interest. Our study highlighted that students who underwent the plastination practical class had higher overall performance and a higher mean post‐test grade than those in the pure theoretical group. A favorable effect of a positive self‐knowledge assessment on the students' performance was found, supporting the self‐efficacy model of human behavior. Thus, the current study provides further evidence to support the use of plastinated specimens as an effective teaching method in countries where dissection is not feasible.

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Towards responsible animal research

Abstract: This article expresses the personal opinion of the authors and does not necessarily reflect the official opinion of the European Commission.

Cited by 23 publications

References 3 publications

Experimentação animal: ética e legislação brasileira

Experimentação animal: ética e legislação brasileira

Ethical to using Rats in the Scientific Researches

Practical anatomy classes: An alternative to improve the learning of middle school students

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