Introduction: This commentary explores modern agronomy concepts aimed at enhancing public health through sustainable and nutrient-rich agricultural practices. We explore various innovative approaches, including precision agriculture, sustainable farming, efficient nutrient management, crop diversity, biofortification, climate-resilient farming, vertical farming and urban agriculture, digital agriculture, and agroecology (see Figure 1). Our commentary delves into each of these modern agronomy practices, unveiling their intricate web and profound implications for public health. We aim to demonstrate the potential of modern agronomy as a catalyst for improving public health and the quality of life for individuals and communities worldwide. These concepts collectively strive to elevate public health by improving food quality, enhancing nutrition, and safeguarding the well-being of individuals and communities. By harnessing these cutting-edge agronomic concepts, we aspire to transform agriculture into a powerful force for improving public health and enhancing overall quality of life. . . .